Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDO2 | P48775 | 1/20 | 0.48 |
| ▸ | CNR2 | P34972 | 4/20 | 0.47 |
| ▸ | EGFR | P00533 | 4/20 | 0.44 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.43 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.42 |
| ▸ | ERN1 | O75460 | 1/20 | 0.42 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.41 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.40 |
| ▸ | GAK | O14976 | 1/20 | 0.40 |
| ▸ | METAP2 | P50579 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31514625 | 0.92 | TDO2 (0.48) | TDO2CNR2EGFRMAP4K4NTRK1 | |
| SCHEMBL31514609 | 0.90 | HTR2A (0.50) | TDO2CNR2EGFRMAP4K4ERN1 | |
| SCHEMBL31514564 | 0.89 | TDO2 (0.48) | TDO2EGFRMAP4K4NTRK1 | |
| SCHEMBL31514559 | 0.88 | MAP4K4 (0.51) | TDO2CNR2EGFRMAP4K4HTR2A | |
| SCHEMBL31514565 | 0.87 | CNR2 (0.54) | TDO2CNR2EGFRMAP4K4HTR2A | |
| SCHEMBL31514567 | 0.86 | EGFR (0.49) | TDO2CNR2EGFRMAP4K4KCNQ3 | |
| SCHEMBL31514623 | 0.85 | CNR2 (0.52) | TDO2CNR2EGFRMAP4K4ERN1 | |
| SCHEMBL31514581 | 0.85 | EGFR (0.54) | CNR2EGFRMAP4K4 | |
| SCHEMBL31514589 | 0.83 | CNR2 (0.54) | CNR2EGFRMAP4K4ERN1 | |
| SCHEMBL31514562 | 0.83 | CNR2 (0.47) | CNR2EGFRMAP4K4ERN1GAK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119912429-A | Quinazoline compound with anti-inflammatory activity or pharmaceutically acceptable salt thereof, pharmaceutical composition and application thereof | 安徽医科大学 | 2025-05-02 | — | — | CN | disclosed |