Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 8/20 | 0.42 |
| ▸ | CRBN | Q96SW2 | 8/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 2/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 2/20 | 0.38 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.38 |
| ▸ | CKS1B | P61024 | 1/20 | 0.38 |
| ▸ | SKP1 | P63208 | 1/20 | 0.38 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.38 |
| ▸ | BTK | Q06187 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30810469 | 0.88 | CRBN (0.35) | DDB1CRBNGAACTSKHSD11B1 | |
| SCHEMBL12367685 | 0.79 | GAA (0.55) | DDB1CRBNGAA | |
| SCHEMBL2176628 | 0.79 | GAA (0.55) | DDB1CRBNGAA | |
| SCHEMBL25169537 | 0.76 | DDB1 (0.59) | DDB1CRBNGAACKS1BSKP1 | |
| SCHEMBL27252628 | 0.73 | DDB1 (0.51) | DDB1CRBNKCNA3 | |
| SCHEMBL24873296 | 0.73 | BTK (0.51) | DDB1CRBNGAABTK | |
| SCHEMBL30796794 | 0.73 | DDB1 (0.51) | DDB1CRBNCKS1BSKP1SKP2 | |
| SCHEMBL26452361 | 0.73 | DDB1 (0.51) | DDB1CRBNCKS1BSKP1SKP2 | |
| SCHEMBL25123847 | 0.72 | CTSK (0.54) | GAACTSKHSD11B1CYP2C9BRD4 | |
| SCHEMBL3841283 | 0.72 | CTSK (0.54) | CTSKHSD11B1CYP2C9BRD4KCNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119630644-A | Bifunctional compounds containing pyrimidine derivatives for degradation of cyclin-dependent kinase 2 via the ubiquitin proteasome pathway | 霖康疗法公司 | 2025-03-14 | — | — | CN | disclosed |