Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPR | P35270 | 6/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TNKS | O95271 | 5/20 | 0.43 |
| ▸ | TNKS2 | Q9H2K2 | 5/20 | 0.43 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.43 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | DCTPP1 | Q9H773 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31516368 | 0.91 | SPR (0.56) | SPRPOLBHPGDTNKSTNKS2 | |
| SCHEMBL22999576 | 0.78 | SPR (0.47) | SPRTNKS2PARP2ADORA1MAPT | |
| SCHEMBL22999917 | 0.77 | SPR (0.46) | SPRTNKS2PARP2ADORA1MAPT | |
| SCHEMBL16711597 | 0.77 | TNKS (0.53) | TNKSTNKS2 | |
| SCHEMBL1081986 | 0.75 | HPGD (0.75) | SPRPOLBHPGDTNKSTNKS2 | |
| SCHEMBL31516387 | 0.75 | MTHFD2 (0.57) | SPRTNKS2PARP2 | |
| SCHEMBL1622066 | 0.74 | SPR (0.46) | SPRTNKS2PARP2MAPT | |
| SCHEMBL1622628 | 0.73 | HTR2C (0.56) | SPRTNKS2PARP2KMT2A | |
| SCHEMBL2456754 | 0.73 | SPR (0.46) | SPRTNKS2PARP2ADORA1MAPT | |
| SCHEMBL13250475 | 0.73 | PARP1 (0.51) | SPRTNKS2PARP2ADORA2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025076226-A1 | FUSED HETEROCYCLES FOR TREATING NEURODEGENERATIVE DISEASES | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2025-04-10 | — | — | WO | disclosed |