SCHEMBL31517602

SCHEMBL31517602

NC(=O)Cc1cnn(-c2nccs2)c1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.34
KMT2A Q03164 2/20 0.34
PPARG P37231 2/20 0.34
MAPK10 P53779 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
RXFP1 Q9HBX9 1/20 0.34
NCOR2 Q9Y618 1/20 0.34
NR3C2 P08235 1/20 0.34
KDM4E B2RXH2 3/20 0.33
MAPT P10636 2/20 0.33
HPGD P15428 2/20 0.33
LMNA P02545 1/20 0.33
POLB P06746 1/20 0.33
GAA P10253 1/20 0.33
NR4A1 P22736 1/20 0.33
MPI P34949 1/20 0.33
RECQL P46063 1/20 0.33
RAB9A P51151 1/20 0.33
ESR2 Q92731 1/20 0.33
KDM4C Q9H3R0 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2529820 0.87 FFAR4 (0.39) ALDH1A1KMT2APPARGMAPK10NPSR1
SCHEMBL24221966 0.80 GABRA1 (0.42) ALDH1A1KMT2APPARGMAPK10NPSR1
SCHEMBL19975267 0.80 PDE10A (0.34) ALDH1A1KMT2APPARGMAPK10NPSR1
SCHEMBL31517219 0.80 ALDH1A1 (0.39) ALDH1A1KMT2APPARGMAPK10NPSR1
Hydrochloric Acid SCHEMBL19975461 0.79 GABRA1 (0.41) ALDH1A1TDP1
SCHEMBL18320461 0.78 ALDH1A1 (0.39) ALDH1A1KMT2APPARGMAPK10NPSR1
SCHEMBL19975093 0.73 KDM4E (0.33) ALDH1A1KDM4E
SCHEMBL3777154 0.73 EGLN1 (0.51) ALDH1A1KMT2APPARGMAPK10NPSR1
SCHEMBL31517647 0.72 MAPT (0.46) ALDH1A1KMT2AKDM4EMAPTHPGD
SCHEMBL30061281 0.72 ALDH1A1 (0.40) ALDH1A1KMT2APPARGMAPK10NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025040546-A1 PYRAZOLE COMPOUNDS AS CULLIN RING UBIQUITIN LIGASE COMPOUNDS PROXYGEN GMBH (AT) 2025-02-27 WO disclosed