SCHEMBL31521561

SCHEMBL31521561

C[Si](C)(C)CCOCn1cnc2ccc3ccccc3c21

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DGAT1 O75907 2/20 0.36
HTT P42858 1/20 0.35
NPC1 O15118 1/20 0.35
KDM4E B2RXH2 1/20 0.35
BRD4 O60885 1/20 0.35
CREBBP Q92793 1/20 0.35
LMNA P02545 2/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
PDE10A Q9Y233 1/20 0.33
AGER Q15109 1/20 0.33
EGFR P00533 1/20 0.33
IGF1R P08069 1/20 0.33
SRC P12931 1/20 0.33
FLT4 P35916 1/20 0.33
KDR P35968 1/20 0.33
FLT3 P36888 1/20 0.33
EPHB4 P54760 1/20 0.33
TEK Q02763 1/20 0.33
KMT2A Q03164 3/20 0.33
CYP3A4 P08684 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15122763 0.77 HTT (0.42) DGAT1HTTNPC1BRD4CREBBP
SCHEMBL22717793 0.77 BRD4 (0.36) DGAT1HTTNPC1BRD4CREBBP
SCHEMBL15845891 0.76 KMT2A (0.52) HTTLMNASMN1; SMN2KMT2ACYP3A4
SCHEMBL31572148 0.76 KMT2A (0.52) HTTLMNASMN1; SMN2KMT2ACYP3A4
SCHEMBL5591449 0.76 LMNA (0.39) DGAT1HTTNPC1BRD4CREBBP
SCHEMBL5082216 0.76 KDM4E (0.42) HTTKDM4EBRD4LMNASMN1; SMN2
SCHEMBL24554516 0.76 POLB (0.37) DGAT1HTTNPC1KDM4ELMNA
SCHEMBL2357255 0.75 SMN1; SMN2 (0.56) HTTNPC1LMNASMN1; SMN2KMT2A
SCHEMBL30013328 0.75 SMN1; SMN2 (0.56) HTTNPC1LMNASMN1; SMN2KMT2A
SCHEMBL9583448 0.75 BRD4 (0.35) DGAT1NPC1BRD4CREBBPLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113347972-B Methods and formulations for treating mitochondrial dysfunction 利兰·斯坦福青年大学托管委员会 2025-04-29 CN disclosed