Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.35 |
| ▸ | DGAT1 | O75907 | 4/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
| ▸ | AKT1 | P31749 | 1/20 | 0.33 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.33 |
| ▸ | FRK | P42685 | 1/20 | 0.33 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.33 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.33 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | PRKD2 | Q9BZL6 | 1/20 | 0.33 |
| ▸ | MAP4K5 | Q9Y4K4 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | IGF1R | P08069 | 1/20 | 0.32 |
| ▸ | SRC | P12931 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9583407 | 0.81 | RPS6KA5 (0.37) | BRD4CREBBPDGAT1CYP11B1CYP11B2 | |
| SCHEMBL17212882 | 0.80 | DGAT1 (0.35) | BRD4CREBBPDGAT1GSK3BLMNA | |
| SCHEMBL4064723 | 0.78 | PTGS2 (0.50) | DGAT1PRKD3MAP4K4FRKMAPK9 | |
| SCHEMBL31469288 | 0.77 | DGAT1 (0.42) | BRD4CREBBPDGAT1PRKD3MAP4K4 | |
| SCHEMBL15122763 | 0.76 | HTT (0.42) | BRD4CREBBPDGAT1LMNASMN1; SMN2 | |
| SCHEMBL31521561 | 0.75 | DGAT1 (0.36) | BRD4CREBBPDGAT1LMNASMN1; SMN2 | |
| SCHEMBL5591449 | 0.74 | LMNA (0.39) | BRD4CREBBPDGAT1CYP11B1CYP11B2 | |
| SCHEMBL4799731 | 0.74 | PTGS2 (0.43) | DGAT1LMNAF11PTGS2NPC1 | |
| SCHEMBL7843607 | 0.74 | ESR1 (0.47) | BRD4DGAT1EGFRIGF1RSRC | |
| SCHEMBL2357255 | 0.73 | SMN1; SMN2 (0.56) | CYP11B1CYP11B2LMNASMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5208242-A | 5-substituted-4-phenyl-5H-imidazo[4,5-c]pyridine derivatives | G. D. SEARLE & CO. (US) | 1993-05-04 | — | — | US | disclosed |