SCHEMBL31521635

SCHEMBL31521635

FC(F)(F)c1coc2c1-c1nn(C[C@H]3COCCO3)cc1CC2

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 1/20 0.32
▸ TP53 P04637 1/20 0.32
▸ MAPT P10636 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31521631 1.00 LMNA (0.32) LMNATP53MAPT
SCHEMBL31521667 0.82 SHMT2 (0.32) LMNATP53MAPT
SCHEMBL31521630 0.81 — —
SCHEMBL31521637 0.81 — —
SCHEMBL31521633 0.81 — —
SCHEMBL31521632 0.81 — —
SCHEMBL23530700 0.77 MAPT (0.45) LMNATP53MAPT
SCHEMBL23552943 0.77 MAPT (0.45) LMNATP53MAPT
SCHEMBL23530528 0.77 MAPT (0.45) LMNATP53MAPT
SCHEMBL30970529 0.76 TP53 (0.35) LMNATP53MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4077334-B1 FUROINDAZOLE DERIVATIVES BAYER AG (DE) 2025-03-12 — — EP claimed
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