SCHEMBL3152179

SCHEMBL3152179

O=C(O)c1n[nH]c(C(=O)O)c1C(=O)O

nearest known ligand 0.42

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 18/20 0.42
KMT2A Q03164 1/20 0.39
TSHR P16473 1/20 0.38
KDM4C Q9H3R0 1/20 0.35
SLC6A4 P31645 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7254688 0.76 KDM4C (0.48) HCAR2KMT2ATSHRKDM4CSLC6A4
SCHEMBL16919030 0.71 KDM4C (0.62) HCAR2KMT2AKDM4C
SCHEMBL8807725 0.67 HCAR2 (0.39) HCAR2KMT2ATSHR
SCHEMBL29956356 0.67 HCAR2 (0.53) HCAR2KMT2ATSHRKDM4C
SCHEMBL28543309 0.66 HCAR2 (0.45) HCAR2KDM4C
SCHEMBL1816267 0.66 HCAR2 (0.50) HCAR2KMT2ATSHRKDM4C
SCHEMBL8805066 0.65 HCAR2 (0.41) HCAR2
SCHEMBL24423821 0.64 HCAR2 (0.59) HCAR2KMT2ATSHRSLC6A4
SCHEMBL8847161 0.62 JAK2 (0.37)
SCHEMBL11029352 0.62 KDM4E (0.54) HCAR2KMT2ATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111004399-A Synthesis method of novel coordination polymer 天津理工大学 2020-04-14 CN claimed
CN-121006246-B High-load motor train unit gearbox lubricating oil and preparation method thereof 孚迪斯石油化工科技(葫芦岛)股份有限公司 2026-03-31 CN disclosed
CN-121006246-A High-load motor train unit gearbox lubricating oil and preparation method thereof 孚迪斯石油化工科技(葫芦岛)股份有限公司 2025-11-25 CN disclosed
CN-111004399-A Synthesis method of novel coordination polymer 天津理工大学 2020-04-14 CN disclosed
EP-2099452-B1 TRICARBONYL COMPLEXES WITH TRIDENTATE CHELATORS FOR MYOCARDIUM IMAGING MALLINCKRODT LLC (US) 2015-07-22 EP disclosed
EP-2099452-B1 TRICARBONYL COMPLEXES WITH TRIDENTATE CHELATORS FOR MYOCARDIUM IMAGING MALLINCKRODT LLC (US) 2015-07-22 EP disclosed
US-9023315-B2 Tricarbonyl complexes with tridentate chelators for myocardium imaging MALLINCKRODT LLC (US) 2015-05-05 US disclosed
US-8940273-B2 Tricarbonyl complexes with tridentate chelators for myocardium imaging MALLINCKRODT LLC (US) 2015-01-27 US disclosed
US-20130129620-A1 Tricarbonyl Complexes with Tridentate Chelators for Myocardium Imaging MALLINCKRODT LLC (US) 2013-05-23 US disclosed
US-20130131327-A1 Tricarbonyl Complexes with Tridentate Chelators for Myocardium Imaging MALLINCKRODT LLC (US) 2013-05-23 US disclosed
US-8372379-B2 Technetium-99m (I) tricarbonyl complexes with tridentate chelators for myocardium imaging MALLINCKRODT LLC (US) 2013-02-12 US disclosed
US-8372379-B2 Technetium-99m (I) tricarbonyl complexes with tridentate chelators for myocardium imaging MALLINCKRODT LLC (US) 2013-02-12 US disclosed
US-20100074842-A1 Technetium-99m (I) Tricarbonyl Complexes with Tridentate Chelators for Myocardium Imaging LIEBEL-FLARSHEIM COMPANY LLC 2010-03-25 US disclosed
EP-2099452-A2 TRICARBONYL COMPLEXES WITH TRIDENTATE CHELATORS FOR MYOCARDIUM IMAGING Mallinckrodt Inc. (US) 2009-09-16 EP disclosed
WO-2008061792-A2 TRICARBONYL COMPLEXES WITH TRIDENTATE CHELATORS FOR MYOCARDIUM IMAGING MALLINCKRODT INC. (US) 2008-05-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130131327-A1 Tricarbonyl Complexes with Tridentate Chelators for Myocardium Imaging TNNT2, TNNI3, FABP3 HCAR2 1314/4885KMT2A 2725/4885TSHR 512/4885
US-20100074842-A1 Technetium-99m (I) Tricarbonyl Complexes with Tridentate Chelators for Myocardium Imaging TNNT2, TNNI3, FABP3 HCAR2 2122/4885KMT2A 3018/4885TSHR 128/4885
US-20130129620-A1 Tricarbonyl Complexes with Tridentate Chelators for Myocardium Imaging TNNT2, TNNI3, FABP3 HCAR2 1314/4885KMT2A 2725/4885TSHR 512/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.