Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Terephthalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | SRD5A2 | P31213 | 3/20 | 0.48 |
| ▸ | CA1 | P00915 | 4/20 | 0.46 |
| ▸ | CA2 | P00918 | 4/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CA3 | P07451 | 2/20 | 0.46 |
| ▸ | CA6 | P23280 | 2/20 | 0.46 |
| ▸ | CA5A | P35218 | 2/20 | 0.46 |
| ▸ | CA7 | P43166 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.46 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.46 |
| ▸ | TYR | P14679 | 1/20 | 0.46 |
| ▸ | DRD1 | P21728 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Terephthalic Acid SCHEMBL31728631 | 0.80 | TSHR (0.67) | TSHRTP53KMT2AALDH1A1SMN1; SMN2 | |
| Terephthalic Acid SCHEMBL31729344 | 0.80 | TSHR (0.67) | TSHRTP53KMT2AALDH1A1SMN1; SMN2 | |
| Terephthalic Acid SCHEMBL23069370 | 0.80 | TSHR (0.75) | TSHRTP53KMT2AALDH1A1SMN1; SMN2 | |
| Terephthalic Acid SCHEMBL28393368 | 0.80 | TSHR (0.75) | TSHRTP53KMT2AALDH1A1SMN1; SMN2 | |
| Terephthalic Acid SCHEMBL23071346 | 0.80 | TSHR (0.75) | TSHRTP53KMT2AALDH1A1SMN1; SMN2 | |
| Terephthalic Acid SCHEMBL4243136 | 0.78 | TSHR (0.71) | TSHRTP53KMT2AALDH1A1SMN1; SMN2 | |
| Terephthalic Acid SCHEMBL338413 | 0.78 | TSHR (0.71) | TSHRTP53KMT2AALDH1A1SMN1; SMN2 | |
| Terephthalic Acid SCHEMBL28509987 | 0.78 | TSHR (0.71) | TSHRTP53KMT2AALDH1A1SMN1; SMN2 | |
| Terephthalic Acid SCHEMBL19665047 | 0.77 | TSHR (0.80) | TSHRTP53ALDH1A1SMN1; SMN2SRD5A2 | |
| Terephthalic Acid SCHEMBL4226573 | 0.77 | TSHR (0.80) | TSHRTP53ALDH1A1SMN1; SMN2SRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119552088-A | Method for recycling polyester through alcohol amine compound high-efficiency selective alcoholysis | 四川大学 | 2025-03-04 | — | — | CN | disclosed |