Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 5/20 | 0.48 |
| ▸ | CA9 | Q16790 | 5/20 | 0.48 |
| ▸ | CA12 | O43570 | 4/20 | 0.48 |
| ▸ | CA4 | P22748 | 1/20 | 0.47 |
| ▸ | PIK3CD | O00329 | 5/20 | 0.47 |
| ▸ | PIK3R1 | P27986 | 5/20 | 0.47 |
| ▸ | PIK3CA | P42336 | 5/20 | 0.47 |
| ▸ | PIK3CB | P42338 | 5/20 | 0.47 |
| ▸ | PIK3CG | P48736 | 5/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 2/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.40 |
| ▸ | SUV39H2 | Q9H5I1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15507834 | 0.77 | ALDH1A1 (0.54) | PIK3CDPIK3R1PIK3CAPIK3CBPIK3CG | |
| SCHEMBL17548211 | 0.77 | SUV39H2 (0.46) | PIK3CDPIK3R1PIK3CAPIK3CBPIK3CG | |
| SCHEMBL31063652 | 0.77 | AAK1 (0.45) | PIK3CDPIK3R1PIK3CAPIK3CBPIK3CG | |
| SCHEMBL4772911 | 0.74 | PDGFRB (0.44) | AAK1SCN9ASUV39H2 | |
| SCHEMBL27372235 | 0.71 | CA2 (0.46) | CA2CA9CA12CA4PIK3CD | |
| SCHEMBL4574087 | 0.71 | MAPK14 (0.46) | CA2CA9CA12PIK3CDPIK3R1 | |
| SCHEMBL10864194 | 0.70 | PKM (0.58) | CA2CA9CA12CA4CA1 | |
| SCHEMBL38653675 | 0.70 | PKM (0.58) | CA2CA9CA12CA4CA1 | |
| SCHEMBL21667913 | 0.69 | TSHR (0.50) | — | |
| SCHEMBL26560458 | 0.68 | HTR1D (0.43) | PIK3CDPIK3CAPIK3CBPIK3CGAAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250122152-A1 | KAT6 Inhibitors | BEIGENE SWITZERLAND GMBH (CH) | 2025-04-17 | — | — | US | disclosed |
| WO-2025068943-A1 | KAT6 INHIBITORS | BEIGENE SWITZERLAND GMBH (CH) | 2025-04-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250122152-A1 | KAT6 Inhibitors | KAT6A, KAT6B, KAT7 | CA2 2848/4885CA9 3240/4885CA12 3152/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.