SCHEMBL31526089

SCHEMBL31526089

Cc1noc(-c2ccccc2)c1CSC[C@H]1O[C@@H](n2cc(Cc3ccccc3)c3c(N)ncnc32)[C@H](O)[C@@H]1O

nearest known ligand 0.45

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ ADK P55263 7/20 0.45
▸ PRMT5 O14744 4/20 0.45
▸ PRMT9 Q6P2P2 1/20 0.45
▸ GNMT Q14749 2/20 0.44
▸ DOT1L Q8TEK3 4/20 0.44
▸ PRMT3 O60678 2/20 0.44
▸ DNMT1 P26358 2/20 0.44
▸ NNMT P40261 1/20 0.44
▸ EHMT2 Q96KQ7 1/20 0.43
▸ NADK O95544 1/20 0.43
▸ METTL3 Q86U44 1/20 0.42
▸ CARM1 Q86X55 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31526111 0.93 ADK (0.44) ADKPRMT5PRMT9GNMTDOT1L
SCHEMBL31526383 0.93 DOT1L (0.47) ADKPRMT5PRMT9GNMTDOT1L
SCHEMBL31526252 0.92 GNMT (0.54) ADKPRMT5PRMT9GNMTDOT1L
SCHEMBL31526297 0.91 ADK (0.45) ADKPRMT5PRMT9GNMTDOT1L
SCHEMBL31526186 0.89 ADK (0.58) ADKPRMT5PRMT9DOT1LPRMT3
SCHEMBL31526238 0.89 PRMT5 (0.42) ADKPRMT5PRMT9GNMTDOT1L
SCHEMBL31526228 0.89 PRMT5 (0.45) ADKPRMT5PRMT9GNMTDOT1L
SCHEMBL31526168 0.89 ADK (0.44) ADKPRMT5PRMT9GNMTDOT1L
SCHEMBL31570710 0.89 ADK (0.47) ADKPRMT5PRMT9GNMTDOT1L
SCHEMBL31526255 0.89 ADK (0.56) ADKPRMT5PRMT9DOT1LPRMT3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025098545-A1 NUCLEOSIDE DERIVATIVES AS ANTIVIRAL AGENTS AGAINST CORONAVIRUSES USTAV ORGANICKE CHEMIE A BIOCHEMIE AV CR, V. V. I. (CZ) 2025-05-15 — — WO disclosed
EP-4553080-A1 NUCLEOSIDE DERIVATIVES AS ANTIVIRAL AGENTS AGAINST CORONAVIRUSES Ustav Organicke Chemie a Biochemie AV CR, v.v.i. (CZ) 2025-05-14 — — EP disclosed
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