SCHEMBL31526252

SCHEMBL31526252

Cc1noc(-c2ccccc2)c1CSC[C@H]1O[C@@H](n2cc(Cc3ccc4ccccc4c3)c3c(N)ncnc32)[C@H](O)[C@@H]1O

nearest known ligand 0.54

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ GNMT Q14749 2/20 0.54
▸ PRMT5 O14744 8/20 0.44
▸ METTL3 Q86U44 8/20 0.43
▸ ADK P55263 2/20 0.42
▸ PRMT9 Q6P2P2 1/20 0.42
▸ DOT1L Q8TEK3 2/20 0.41
▸ NADK O95544 1/20 0.41
▸ PRMT3 O60678 1/20 0.41
▸ DNMT1 P26358 1/20 0.41
▸ NNMT P40261 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31526089 0.92 ADK (0.45) GNMTPRMT5METTL3ADKPRMT9
SCHEMBL31526236 0.89 ADK (0.52) GNMTPRMT5METTL3ADKDOT1L
SCHEMBL31526383 0.88 DOT1L (0.47) GNMTPRMT5ADKPRMT9DOT1L
SCHEMBL31526111 0.88 ADK (0.44) GNMTPRMT5METTL3ADKPRMT9
SCHEMBL31570705 0.87 GNMT (0.39) GNMTPRMT5METTL3PRMT9
SCHEMBL31526297 0.86 ADK (0.45) GNMTPRMT5ADKPRMT9DOT1L
SCHEMBL31526392 0.85 ADK (0.49) GNMTPRMT5ADKPRMT9DOT1L
SCHEMBL31526186 0.85 ADK (0.58) PRMT5ADKPRMT9DOT1LNADK
SCHEMBL31526228 0.85 PRMT5 (0.45) GNMTPRMT5ADKPRMT9DOT1L
SCHEMBL31526255 0.84 ADK (0.56) PRMT5ADKPRMT9DOT1LNADK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025098545-A1 NUCLEOSIDE DERIVATIVES AS ANTIVIRAL AGENTS AGAINST CORONAVIRUSES USTAV ORGANICKE CHEMIE A BIOCHEMIE AV CR, V. V. I. (CZ) 2025-05-15 — — WO disclosed
EP-4553080-A1 NUCLEOSIDE DERIVATIVES AS ANTIVIRAL AGENTS AGAINST CORONAVIRUSES Ustav Organicke Chemie a Biochemie AV CR, v.v.i. (CZ) 2025-05-14 — — EP disclosed
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