SCHEMBL31526164

SCHEMBL31526164

CCOC(=O)c1c(-c2ccccc2)csc1C

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 7/20 0.62
GSTO1 P78417 1/20 0.62
ALDH1A1 P00352 9/20 0.60
MAPT P10636 6/20 0.60
SMN1; SMN2 Q16637 5/20 0.60
MEN1 O00255 3/20 0.60
KMT2A Q03164 3/20 0.60
ALOX12 P18054 2/20 0.60
HTT P42858 2/20 0.60
POLB P06746 3/20 0.59
RAB9A P51151 2/20 0.59
PRKCZ Q05513 4/20 0.58
PTPRC P08575 1/20 0.58
PTPRF P10586 1/20 0.58
PTPN2 P17706 1/20 0.58
PTPN1 P18031 1/20 0.58
PTPA Q15257 1/20 0.58
L3MBTL1 Q9Y468 1/20 0.58
HPGD P15428 5/20 0.57
HSD17B10 Q99714 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31618843 0.88 LMNA (0.62) LMNAGSTO1ALDH1A1MAPTSMN1; SMN2
SCHEMBL1190649 0.85 PRKCZ (0.80) LMNAGSTO1ALDH1A1MAPTMEN1
SCHEMBL23599197 0.83 LMNA (0.74) LMNAGSTO1ALDH1A1MAPTSMN1; SMN2
SCHEMBL689452 0.83 PRKCZ (0.80) LMNAALDH1A1MAPTMEN1KMT2A
SCHEMBL11634946 0.81 LMNA (0.74) LMNAGSTO1ALDH1A1MAPTSMN1; SMN2
SCHEMBL13712822 0.80 KMT2A (0.52) LMNAGSTO1ALDH1A1MAPTSMN1; SMN2
SCHEMBL23580345 0.80 LMNA (0.73) LMNAGSTO1ALDH1A1MAPTSMN1; SMN2
SCHEMBL26038505 0.79 KMT2A (0.50) LMNAGSTO1ALDH1A1MAPTSMN1; SMN2
SCHEMBL18803865 0.79 ALDH1A1 (0.59) LMNAALDH1A1MAPTSMN1; SMN2MEN1
SCHEMBL9396589 0.79 LMNA (0.79) LMNAGSTO1ALDH1A1MAPTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025098545-A1 NUCLEOSIDE DERIVATIVES AS ANTIVIRAL AGENTS AGAINST CORONAVIRUSES USTAV ORGANICKE CHEMIE A BIOCHEMIE AV CR, V. V. I. (CZ) 2025-05-15 WO disclosed
EP-4553080-A1 NUCLEOSIDE DERIVATIVES AS ANTIVIRAL AGENTS AGAINST CORONAVIRUSES Ustav Organicke Chemie a Biochemie AV CR, v.v.i. (CZ) 2025-05-14 EP disclosed