SCHEMBL31526178

Cc1noc(-c2ccccc2)c1CSC[C@H]1O[C@@H](n2cc(/C=C/c3ccccc3)c3c(N)ncnc32)[C@H](O[Si](C)(C)C(C)(C)C)[C@@H]1O[Si](C)(C)C(C)(C)C

nearest known ligand 0.33

Predicted protein targets (top 10)

	gene	UniProt	supporting neighbours	confidence
▸	PRMT5	O14744	3/20	0.33

▸	PRMT9	Q6P2P2	1/20	0.33

▸	ADK	P55263	3/20	0.33

▸	METTL3	Q86U44	1/20	0.31

▸	NADK	O95544	1/20	0.31

▸	DOT1L	Q8TEK3	2/20	0.30

▸	PRMT3	O60678	1/20	0.30

▸	DNMT1	P26358	1/20	0.30

▸	NNMT	P40261	1/20	0.30

▸	P2RY12	Q9H244	1/20	0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL31526145	0.95	PRMT5 (0.32)	PRMT5PRMT9ADKMETTL3NNMT
SCHEMBL31526198	0.92	PRMT5 (0.34)	PRMT5PRMT9ADKMETTL3NADK
SCHEMBL31526181	0.89	ADK (0.41)	PRMT5PRMT9ADKDOT1LPRMT3
SCHEMBL31526088	0.88	ADK (0.36)	PRMT5PRMT9ADKMETTL3NADK
SCHEMBL31526233	0.87	DOT1L (0.43)	PRMT5PRMT9ADKNADKDOT1L
SCHEMBL31526221	0.87	PRMT5 (0.34)	PRMT5PRMT9ADKNADKDOT1L
SCHEMBL31526395	0.86	PRMT5 (0.35)	PRMT5PRMT9ADKMETTL3NADK
SCHEMBL31526128	0.86	ADK (0.33)	PRMT5PRMT9ADKNADKDOT1L
SCHEMBL31526151	0.86	PRMT5 (0.35)	PRMT5PRMT9ADKNADKDOT1L
SCHEMBL31526176	0.86	ADK (0.44)	PRMT5PRMT9ADKMETTL3NADK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2025098545-A1	NUCLEOSIDE DERIVATIVES AS ANTIVIRAL AGENTS AGAINST CORONAVIRUSES	USTAV ORGANICKE CHEMIE A BIOCHEMIE AV CR, V. V. I. (CZ)	2025-05-15	—	—	WO	disclosed