SCHEMBL31526308

SCHEMBL31526308

Cc1noc(-c2ccccc2)c1CSC[C@H]1O[C@@H](n2cc(C3CCCCC3)c3c(N)ncnc32)[C@H](O[Si](C)(C)C(C)(C)C)[C@@H]1O[Si](C)(C)C(C)(C)C

nearest known ligand 0.41

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ METTL3 Q86U44 13/20 0.41
▸ PRMT5 O14744 11/20 0.39
▸ WDR77 Q9BQA1 1/20 0.34
▸ ABL1 P00519 2/20 0.33
▸ EGFR P00533 2/20 0.33
▸ SRC P12931 2/20 0.33
▸ ABL2 P42684 2/20 0.33
▸ PRMT9 Q6P2P2 1/20 0.33
▸ IGF1R P08069 1/20 0.32
▸ ADK P55263 1/20 0.32
▸ LCK P06239 1/20 0.32
▸ KDR P35968 1/20 0.32
▸ TEK Q02763 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31526358 0.99 METTL3 (0.40) METTL3PRMT5WDR77ABL1EGFR
SCHEMBL31526254 0.90 PRMT5 (0.41) METTL3PRMT5ABL1EGFRSRC
SCHEMBL31570699 0.88 PRMT5 (0.31) METTL3PRMT5PRMT9ADK
SCHEMBL31526181 0.88 ADK (0.41) PRMT5PRMT9ADK
SCHEMBL31526088 0.88 ADK (0.36) METTL3PRMT5PRMT9ADK
SCHEMBL31526128 0.87 ADK (0.33) PRMT5PRMT9ADK
SCHEMBL31526221 0.86 PRMT5 (0.34) PRMT5PRMT9ADK
SCHEMBL31526198 0.86 PRMT5 (0.34) METTL3PRMT5PRMT9ADK
SCHEMBL31526233 0.86 DOT1L (0.43) PRMT5PRMT9ADK
SCHEMBL31526239 0.86 METTL3 (0.52) METTL3PRMT5WDR77PRMT9ADK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025098545-A1 NUCLEOSIDE DERIVATIVES AS ANTIVIRAL AGENTS AGAINST CORONAVIRUSES USTAV ORGANICKE CHEMIE A BIOCHEMIE AV CR, V. V. I. (CZ) 2025-05-15 — — WO disclosed
EP-4553080-A1 NUCLEOSIDE DERIVATIVES AS ANTIVIRAL AGENTS AGAINST CORONAVIRUSES Ustav Organicke Chemie a Biochemie AV CR, v.v.i. (CZ) 2025-05-14 — — EP disclosed
Send feedback