Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 4/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.39 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31529226 | 0.88 | ADORA1 (0.36) | ADORA1ADORA2ANPC1CCNA2CDK2 | |
| SCHEMBL31529155 | 0.83 | ADORA1 (0.43) | ADORA1ADORA2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL31529339 | 0.79 | ADORA1 (0.36) | ADORA1ADORA2ACCNA2CDK2CDK5 | |
| SCHEMBL31529303 | 0.77 | NPC1 (0.40) | NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL31529197 | 0.77 | PAX8 (0.50) | NPC1SMN1; SMN2 | |
| SCHEMBL31529135 | 0.77 | KDM4E (0.40) | NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL31529108 | 0.77 | ADORA1 (0.43) | ADORA1ADORA2ACCNA2CDK2CDK5 | |
| SCHEMBL31529128 | 0.76 | L3MBTL1 (0.41) | NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL17009435 | 0.72 | CYP2C19 (0.54) | ADORA1ADORA2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL31529201 | 0.72 | NPC1 (0.47) | ADORA1ADORA2ANPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025090774-A1 | CHEMOTHERAPEUTIC COMPOUNDS AND METHODS OF USE | SEAGEN INC. (US) | 2025-05-01 | — | — | WO | disclosed |