Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 3/20 | 0.36 |
| ▸ | JAK2 | O60674 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | SCN4A | P35499 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.34 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | JAK3 | P52333 | 2/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31529339 | 0.91 | ADORA1 (0.36) | ADORA1CCNA2CDK2CDK5CDK5R1 | |
| SCHEMBL31529233 | 0.88 | ADORA1 (0.44) | ADORA1CCNA2CDK2CDK5CDK5R1 | |
| SCHEMBL31529128 | 0.77 | L3MBTL1 (0.41) | JAK2KDM4EPOLBSCN4AL3MBTL1 | |
| SCHEMBL31529197 | 0.76 | PAX8 (0.50) | JAK2KDM4EPOLBSCN4AL3MBTL1 | |
| SCHEMBL31529303 | 0.76 | NPC1 (0.40) | JAK2KDM4EPOLBSCN4AL3MBTL1 | |
| SCHEMBL31529135 | 0.76 | KDM4E (0.40) | JAK2KDM4EPOLBSCN4AL3MBTL1 | |
| SCHEMBL31529108 | 0.71 | ADORA1 (0.43) | ADORA1CCNA2CDK2CDK5CDK5R1 | |
| SCHEMBL31529155 | 0.71 | ADORA1 (0.43) | ADORA1NPC1ADORA2A | |
| SCHEMBL31529164 | 0.70 | PAX8 (0.43) | ADORA1JAK2KDM4EPOLBSCN4A | |
| SCHEMBL31529316 | 0.70 | PAX8 (0.43) | ADORA1JAK2KDM4EPOLBSCN4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025090774-A1 | CHEMOTHERAPEUTIC COMPOUNDS AND METHODS OF USE | SEAGEN INC. (US) | 2025-05-01 | — | — | WO | disclosed |