Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.46 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.44 |
| ▸ | IKBKB | O14920 | 4/20 | 0.44 |
| ▸ | MPO | P05164 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | DCPS | Q96C86 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31530990 | 0.77 | CYP1A2 (0.46) | CYP11B1CYP11B2IKBKBCYP3A4CYP2C9 | |
| SCHEMBL29043927 | 0.77 | IKBKB (0.59) | CYP19A1CYP11B1CYP11B2LTA4HMAPK14 | |
| SCHEMBL1937025 | 0.75 | LTA4H (0.56) | CYP19A1CYP11B1CYP11B2LTA4HMAPK14 | |
| SCHEMBL31002058 | 0.73 | PRMT5 (0.45) | LTA4HMAPK14MPOCYP3A4ALDH1A1 | |
| SCHEMBL30150617 | 0.73 | ABCB1 (0.54) | CYP19A1CYP11B1CYP11B2LTA4HMAPK14 | |
| SCHEMBL27655217 | 0.72 | LTA4H (0.56) | CYP19A1CYP11B1CYP11B2LTA4HMAPK14 | |
| SCHEMBL31192966 | 0.72 | DYRK1A (0.36) | LTA4HMAPK14MPO | |
| SCHEMBL6644771 | 0.70 | LTA4H (0.49) | LTA4HMAPK14MPOIDO1CYP3A4 | |
| SCHEMBL8210963 | 0.70 | BRD4 (0.53) | LTA4HMAPK14IDO1PTGER1CYP3A4 | |
| SCHEMBL31530991 | 0.69 | NUDT1 (0.40) | CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119912478-A | Amino heteroaryl macrocyclic compounds, preparation method and application thereof | 北京鞍石生物科技股份有限公司 | 2025-05-02 | — | — | CN | disclosed |