Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.36 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.36 |
| ▸ | ATP4A | P20648 | 2/20 | 0.35 |
| ▸ | ATP4B | P51164 | 2/20 | 0.35 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | KDM5A | P29375 | 1/20 | 0.34 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | MPO | P05164 | 1/20 | 0.34 |
| ▸ | TLR4 | O00206 | 1/20 | 0.33 |
| ▸ | TLR3 | O15455 | 1/20 | 0.33 |
| ▸ | TLR5 | O60602 | 1/20 | 0.33 |
| ▸ | TLR2 | O60603 | 1/20 | 0.33 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.33 |
| ▸ | CAMK2G | Q13555 | 1/20 | 0.33 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31002058 | 0.86 | PRMT5 (0.45) | DYRK1ADYRK2DYRK1BATP4AATP4B | |
| SCHEMBL31002417 | 0.85 | ADORA2A (0.34) | DYRK1ADYRK2DYRK1BADORA2AATP4A | |
| SCHEMBL31002485 | 0.83 | ALKBH1 (0.39) | DYRK1ADYRK2DYRK1BATP4AATP4B | |
| SCHEMBL30688977 | 0.80 | ADORA2A (0.32) | ADORA2A | |
| SCHEMBL29127729 | 0.80 | ADORA2A (0.32) | ADORA2A | |
| SCHEMBL31192836 | 0.75 | CYP11B2 (0.35) | ADORA2AADORA3 | |
| SCHEMBL31530982 | 0.72 | CYP19A1 (0.46) | LTA4HMAPK14MPO | |
| SCHEMBL31192827 | 0.72 | CYP1A2 (0.39) | MAPK14TSHR | |
| SCHEMBL31002367 | 0.71 | ATP4A (0.40) | DYRK1ADYRK2DYRK1BADORA2AATP4A | |
| SCHEMBL31192978 | 0.70 | PRMT5 (0.46) | DYRK1ADYRK2DYRK1BATP4AATP4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4658662-A1 | MACROCYCLIC AMINOPYRIDINE COMPOUNDS AS EGFR INHIBITORS | Yuhan Corporation (KR) | 2025-12-10 | — | — | EP | disclosed |
| WO-2024177360-A1 | MACROCYCLIC AMINOPYRIDINE COMPOUNDS AS EGFR INHIBITORS | YUHAN CORPORATION (KR) | 2024-08-29 | — | — | WO | disclosed |