Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 9/20 | 0.56 |
| ▸ | FLT3 | P36888 | 7/20 | 0.56 |
| ▸ | KIT | P10721 | 7/20 | 0.56 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.41 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.41 |
| ▸ | AURKB | Q96GD4 | 4/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.41 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.41 |
| ▸ | PIM1 | P11309 | 2/20 | 0.41 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.41 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.41 |
| ▸ | PRKACA | P17612 | 2/20 | 0.41 |
| ▸ | LTK | P29376 | 2/20 | 0.41 |
| ▸ | GRK5 | P34947 | 2/20 | 0.41 |
| ▸ | CDK8 | P49336 | 2/20 | 0.41 |
| ▸ | CDK7 | P50613 | 2/20 | 0.41 |
| ▸ | CDK9 | P50750 | 2/20 | 0.41 |
| ▸ | LIMK1 | P53667 | 2/20 | 0.41 |
| ▸ | MAP2K1 | Q02750 | 2/20 | 0.41 |
| ▸ | ACVR1 | Q04771 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6930697 | 0.89 | KDR (0.46) | KDRFLT3KITAURKBMAP4K4 | |
| SCHEMBL9905767 | 0.85 | KDR (0.43) | KDRFLT3KITNCOA1NCOA3 | |
| SCHEMBL2876990 | 0.79 | KDR (0.47) | KDRFLT3KITAURKBMAP4K4 | |
| SCHEMBL1781983 | 0.77 | KDR (0.50) | KDRFLT3KITAURKBMAP4K4 | |
| SCHEMBL1782135 | 0.73 | KDR (0.46) | KDRFLT3KITAURKBMAP4K4 | |
| SCHEMBL31432578 | 0.73 | KDR (0.46) | KDRFLT3KITAURKBMAP4K4 | |
| SCHEMBL1782232 | 0.73 | KDR (0.46) | KDRFLT3KITAURKBMAP4K4 | |
| SCHEMBL9900752 | 0.73 | ALDH1A1 (0.41) | NCOA1NCOA3MAP4K4ALDH1A1MEN1 | |
| SCHEMBL423711 | 0.72 | KDR (1.00) | KDRFLT3KITAURKBMAP4K4 | |
| SCHEMBL10422418 | 0.71 | KDR (0.44) | KDRFLT3KITAURKBMAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119638639-A | Biaryl compound with anti-cell necrotic apoptosis activity, derivative and application thereof | 中国药科大学 | 2025-03-18 | — | — | CN | disclosed |