Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM4 | Q14833 | 14/20 | 0.37 |
| ▸ | ATR | Q13535 | 2/20 | 0.33 |
| ▸ | ATRIP | Q8WXE1 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.31 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27193526 | 1.00 | GRM4 (0.37) | GRM4ATRATRIPKDM4EALDH1A1 | |
| SCHEMBL27193702 | 1.00 | GRM4 (0.37) | GRM4ATRATRIPKDM4EALDH1A1 | |
| SCHEMBL27193600 | 0.81 | GRM4 (0.34) | GRM4ATRATRIPDGAT1 | |
| SCHEMBL27193380 | 0.80 | DGAT1 (0.36) | DGAT1 | |
| SCHEMBL27193468 | 0.79 | DGAT1 (0.37) | DGAT1 | |
| SCHEMBL31533714 | 0.78 | PDE1B (0.45) | GRM4GPR84 | |
| SCHEMBL27193665 | 0.78 | PDE1B (0.45) | GRM4GPR84 | |
| SCHEMBL27193403 | 0.78 | PDE1B (0.45) | GRM4GPR84 | |
| SCHEMBL24566902 | 0.75 | DGAT1 (0.36) | DGAT1 | |
| SCHEMBL29705582 | 0.75 | DGAT1 (0.36) | DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119654314-A | Heterocyclic amide and urea compounds as JAK2 inhibitors | 艾捷斯治疗公司 | 2025-03-18 | — | — | CN | disclosed |