⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2360465 | 0.93 | GABRR1 (0.39) | — | |
| SCHEMBL22339943 | 0.80 | — | — | |
| SCHEMBL10412398 | 0.80 | ALDH1A1 (0.35) | — | |
| SCHEMBL652869 | 0.80 | — | — | |
| SCHEMBL9416705 | 0.79 | — | — | |
| SCHEMBL791253 | 0.77 | — | — | |
| SCHEMBL2599566 | 0.77 | — | — | |
| SCHEMBL21085104 | 0.77 | — | — | |
| SCHEMBL17164603 | 0.77 | CYP1A2 (0.55) | — | |
| SCHEMBL9328436 | 0.77 | GABRR1 (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106518850-A | Chemical synthesis method of Pimobendan | 青岛农业大学 | 2017-03-22 | — | — | CN | disclosed |
| EP-2755960-B1 | PLANT GROWTH REGULATING COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2016-06-08 | — | — | EP | disclosed |
| US-9345244-B2 | Plant growth regulating compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2016-05-24 | — | — | US | disclosed |
| US-9241489-B2 | Plant growth regulating compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2016-01-26 | — | — | US | disclosed |
| US-20150005167-A1 | PLANT GROWTH REGULATING COMPOUNDS | SYNGENTA LIMITED (GB) | 2015-01-01 | — | — | US | disclosed |
| US-20140371073-A1 | PLANT GROWTH REGULATING COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2014-12-18 | — | — | US | disclosed |
| WO-2014131732-A2 | PLANT GROWTH REGULATING COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2014-09-04 | — | — | WO | disclosed |
| WO-2014122065-A1 | 2-AMINOPYRIDINE DERIVATIVES AS PLANT GROWTH REGULATING COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2014-08-14 | — | — | WO | disclosed |
| EP-2762468-A1 | 2-aminopyridine derivatives as plant growth regulating compounds | Syngenta Participations AG. (CH) | 2014-08-06 | — | — | EP | disclosed |
| EP-2755960-A1 | PLANT GROWTH REGULATING COMPOUNDS | Syngenta Participations AG (CH) | 2014-07-23 | — | — | EP | disclosed |
| CN-1656078-A | Aminoindazole derivatives as protein kinase inhibitors | AVENTIS PHARMA SA (FR) | 2005-08-17 | — | — | CN | disclosed |
| US-20050113366-A1 | Derivatives of 4-hydroxybutanoic acid and of its higher homologue as ligands of $g(g)-hydroxybutyrate (ghb) receptors, pharmaceutical compositions containing same and pharmaceutical uses | UNIVERSITE LOUIS PASTEUR (ETABLISSEMENT PUBLIC A CARACTERE SCIENTIFIQUE, CULTUREL ET PROFESSIONNEL) (FR) | 2005-05-26 | — | — | US | disclosed |
| EP-1363902-B1 | CHEMICAL COMPOUNDS | ASTRAZENECA AB (SE) | 2004-09-15 | — | — | EP | disclosed |
| US-20040102483-A1 | Chemical compounds | ASTRAZENECA AB (SE) | 2004-05-27 | — | — | US | disclosed |
| EP-1363902-A1 | CHEMICAL COMPOUNDS | AstraZeneca AB (SE) | 2003-11-26 | — | — | EP | disclosed |
| EP-1347950-A1 | DERIVATIVES OF 4-HYDROXYBUTANOIC ACID AND OF ITS HIGHER HOMOLOGUE AS LIGANDS OF GAMMA-HYDROXYBUTYRATE (GHB) RECEPTORS, PHARMACEUTICAL COMPOSITIONS CONTAINING SAME AND PHARMACEUTICAL USES | Université Louis Pasteur, (Etablissement public à caractère scientifique, culturel et professionnel) (FR) | 2003-10-01 | — | — | EP | disclosed |
| WO-2002066460-A1 | CHEMICAL COMPOUNDS | ASTRAZENECA AB (SE) | 2002-08-29 | — | — | WO | disclosed |
| WO-2002042250-A1 | DERIVATIVES OF 4-HYDROXYBUTANOIC ACID AND OF ITS HIGHER HOMOLOGUE AS LIGANDS OF η-HYDROXYBUTYRATE (GHB) RECEPTORS, PHARMACEUTICAL COMPOSITIONS CONTAINING SAME AND PHARMACEUTICAL USES | UNIVERSITE LOUIS PASTEUR (ETABLISSEMENT PUBLIC A CARACTERE SCIENTIFIQUE, CULTUREL ET PROFESSIONNEL) (FR) | 2002-05-30 | — | — | WO | disclosed |
| EP-0174271-B1 | ANTHRACEME DERIVATIVES | CIBA-GEIGY AG (CH) | 1991-10-16 | — | — | EP | disclosed |
| EP-0174271-A2 | Anthraceme derivatives | CIBA-GEIGY AG (CH) | 1986-03-12 | — | — | EP | disclosed |