Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | APEX1 | P27695 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.33 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.31 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.31 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.31 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.31 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27033081 | 0.85 | CYP1A2 (0.42) | GLAMAPK1CYP1A2SMN1; SMN2LMNA | |
| SCHEMBL31270233 | 0.82 | L3MBTL1 (0.47) | GLAL3MBTL3L3MBTL1 | |
| SCHEMBL28518764 | 0.79 | HSD17B10 (0.47) | GLAITGB3ITGA2BHSD17B10ALDH1A1 | |
| SCHEMBL9939528 | 0.74 | KDM4E (0.41) | L3MBTL3L3MBTL1ALDH1A1MAPTKMT2A | |
| SCHEMBL19128277 | 0.74 | L3MBTL3 (0.34) | L3MBTL3L3MBTL1 | |
| SCHEMBL3409970 | 0.72 | GLA (0.45) | GLAAPEX1MAPK1CYP1A2SMN1; SMN2 | |
| SCHEMBL15043614 | 0.71 | APEX1 (0.51) | GLAAPEX1MAPK1CYP1A2SMN1; SMN2 | |
| SCHEMBL14967879 | 0.71 | L3MBTL3 (0.33) | L3MBTL3L3MBTL1 | |
| SCHEMBL17792881 | 0.71 | CYP1A2 (0.55) | GLAMAPK1CYP1A2SMN1; SMN2ITGB3 | |
| SCHEMBL12674082 | 0.70 | L3MBTL3 (0.34) | L3MBTL3L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025080946-A2 | RAS INHIBITORS | Revolution Medicines, Inc. (US) | 2025-04-17 | — | — | WO | disclosed |