Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | SLC6A1 | P30531 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ACE | P12821 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | REN | P00797 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PEPD | P12955 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | THPO | P40225 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2158601 | 1.00 | SMN1; SMN2 (0.49) | SMN1; SMN2ALDH1A1SLC6A1L3MBTL1ACE | |
| SCHEMBL5434462 | 1.00 | SMN1; SMN2 (0.49) | SMN1; SMN2ALDH1A1SLC6A1L3MBTL1ACE | |
| SCHEMBL18389489 | 0.98 | SMN1; SMN2 (0.48) | SMN1; SMN2ALDH1A1SLC6A1L3MBTL1ACE | |
| Hydrochloric Acid SCHEMBL5716991 | 0.98 | SMN1; SMN2 (0.48) | SMN1; SMN2ALDH1A1SLC6A1L3MBTL1ACE | |
| Hydrochloric Acid SCHEMBL5717003 | 0.98 | SMN1; SMN2 (0.48) | SMN1; SMN2ALDH1A1SLC6A1L3MBTL1ACE | |
| SCHEMBL151569 | 0.94 | ALDH1A1 (0.47) | SMN1; SMN2ALDH1A1L3MBTL1ACELMNA | |
| SCHEMBL151570 | 0.94 | ALDH1A1 (0.47) | SMN1; SMN2ALDH1A1L3MBTL1ACELMNA | |
| SCHEMBL2275704 | 0.94 | ALDH1A1 (0.47) | SMN1; SMN2ALDH1A1L3MBTL1ACELMNA | |
| Ammonia Solution, Strong SCHEMBL5017115 | 0.92 | ALDH1A1 (0.46) | SMN1; SMN2ALDH1A1L3MBTL1ACELMNA | |
| Hydrochloric Acid SCHEMBL9148101 | 0.92 | ALDH1A1 (0.46) | SMN1; SMN2ALDH1A1L3MBTL1ACELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 77 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130046077-A1 | DOLASTATIN 15 DERIVATIVES | ABBVIE DEUTSCHLAND GMBH & CO KG (DE) | 2013-02-21 | — | — | US | claimed |
| US-20100099843-A1 | DOLASTATIN 15 DERIVATIVES | ABBOTT GMBH & CO. KG (DE) | 2010-04-22 | — | — | US | claimed |
| EP-0471592-B1 | Process for absorption of sulfur compounds from fluids using certain piperidines, piperazines, or anhydrides of monocarboxylic amino acids | DOW CHEMICAL CO (US) | 1995-08-09 | — | — | EP | claimed |
| CN-113993850-B | Modulators of integrated stress response pathways | 埃沃特克国际有限责任公司 | 2024-03-29 | — | — | CN | disclosed |
| WO-2023116856-A1 | AROMATIC VINYL COMPOUND, METAL COMPLEX THEREOF, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海再极医药科技有限公司 | 2023-06-29 | — | — | WO | disclosed |
| WO-2023006019-A1 | POLYSUBSTITUTED BENZENE PD-L1 INHIBITOR, COMPOSITION AND USE THEREOF | 杭州和正医药有限公司 | 2023-02-02 | — | — | WO | disclosed |
| WO-2021093817-A1 | IMMUNOMODULATORY COMPOUNDS, COMPOSITION AND APPLICATION THEREOF | 杭州和正医药有限公司 | 2021-05-20 | — | — | WO | disclosed |
| CN-105073757-B | Dyeing process using a hair-dyeing precursor obtained from an iridoid, composition, precursor and device comprising such a precursor | 莱雅公司 | 2019-12-17 | — | — | CN | disclosed |
| WO-2019046330-A1 | SPIROCYCLE COMPOUNDS AND METHODS OF MAKING AND USING SAME | ABIDE THERAPEUTICS, INC. (US) | 2019-03-07 | — | — | WO | disclosed |
| US-20160046625-A1 | BENZIMIDAZOLE AND AZABENZIMIDAZOLE COMPOUNDS THAT INHIBIT ANAPLASTIC LYMPHOMA KINASE | AMGEN INC (US) | 2016-02-18 | — | — | US | disclosed |
| CN-105073723-A | Compounds derived from protected or unprotected iridoids, compositions comprising same, use as dyes for keratin fibres and devices | OREAL | 2015-11-18 | — | — | CN | disclosed |
| EP-0296416-B1 | BENZO-ANELLATED CYCLIC COMPOUNDS | NIHON BAYER AGROCHEM K.K. (JP) | 1992-07-29 | — | — | EP | disclosed |
| EP-0230874-B1 | BENZOTHIAZOLYLAZOLIDINES, AND THEIR PRODUCTION AND USE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1991-11-27 | — | — | EP | disclosed |
| US-4898948-A | HERBICIDES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1990-02-06 | — | — | US | disclosed |
| EP-0337151-A2 | N-substituted phenyl-heterocyclic compounds | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1989-10-18 | — | — | EP | disclosed |
| US-4828605-A | HERBICIDES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1989-05-09 | — | — | US | disclosed |
| EP-0296416-A1 | Benzo-anellated cyclic compounds | NIHON BAYER AGROCHEM K.K. (JP) | 1988-12-28 | — | — | EP | disclosed |
| US-4786310-A | HERBICIDES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1988-11-22 | — | — | US | disclosed |
| EP-0230874-A1 | Benzothiazolylazolidines, and their production and use | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1987-08-05 | — | — | EP | disclosed |
| US-4125604-A | PEPTIDES, ANTITHROMBOSIS | MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) | 1978-11-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160046625-A1 | BENZIMIDAZOLE AND AZABENZIMIDAZOLE COMPOUNDS THAT INHIBIT ANAPLASTIC LYMPHOMA KINASE | BCL6, DCK, FLI1 | SMN1; SMN2 4299/4885ALDH1A1 607/4885SLC6A1 3395/4885 |
| US-20100099843-A1 | DOLASTATIN 15 DERIVATIVES | DDOST, DBI, DAO | SMN1; SMN2 4192/4885ALDH1A1 1830/4885SLC6A1 3363/4885 |
| US-20130046077-A1 | DOLASTATIN 15 DERIVATIVES | DDOST, DBI, DAO | SMN1; SMN2 4192/4885ALDH1A1 1830/4885SLC6A1 3363/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.