Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.32 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25206036 | 0.82 | LMNA (0.40) | MAPTSMN1; SMN2TSHRCYP1A2CYP2D6 | |
| SCHEMBL18961127 | 0.74 | NPSR1 (0.49) | MAPTCYP1A2ALDH1A1RAB9ANPC1 | |
| SCHEMBL17008544 | 0.72 | SIRT6 (0.44) | SMN1; SMN2TSHRCYP1A2CYP2D6ALDH1A1 | |
| SCHEMBL29546318 | 0.72 | SIRT6 (0.44) | SMN1; SMN2TSHRCYP1A2CYP2D6ALDH1A1 | |
| SCHEMBL20225755 | 0.71 | SIRT6 (0.41) | MAPTCYP1A2CYP2D6ALDH1A1RAB9A | |
| SCHEMBL1563114 | 0.71 | BDKRB2 (0.37) | MAPTTSHRALDH1A1NPC1LMNA | |
| SCHEMBL29546939 | 0.71 | STK17B (0.45) | LMNAMAPK1POLB | |
| SCHEMBL18567056 | 0.71 | STK17B (0.45) | LMNAMAPK1POLB | |
| SCHEMBL1565166 | 0.70 | BDKRB2 (0.38) | MAPTTSHRALDH1A1NPC1LMNA | |
| SCHEMBL20209641 | 0.70 | SIRT6 (0.40) | SMN1; SMN2ALDH1A1SIRT6LMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119684317-A | Macrocyclic compound and application thereof | 郑州德迈药业有限公司 | 2025-03-25 | — | — | CN | disclosed |