Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CRHBP | P24387 | 1/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13990317 | 0.78 | CRHBP (0.39) | TSHRCYP3A4CRHBPCRHR2 | |
| SCHEMBL10748633 | 0.78 | XPO1 (0.41) | TSHRCYP3A4CRHBPCRHR2TDP1 | |
| SCHEMBL10643647 | 0.73 | CYP3A4 (0.38) | TSHRCYP3A4 | |
| SCHEMBL11074204 | 0.72 | CRHBP (0.32) | CRHBPCRHR2 | |
| SCHEMBL10669992 | 0.68 | CYP3A4 (0.33) | TSHRCYP3A4 | |
| SCHEMBL29391823 | 0.67 | — | — | |
| SCHEMBL3363278 | 0.67 | — | — | |
| SCHEMBL28576196 | 0.65 | — | — | |
| SCHEMBL3257764 | 0.65 | TDP1 (0.39) | TSHRCYP3A4LMNATDP1 | |
| SCHEMBL3148909 | 0.65 | TDP1 (0.33) | TSHRCYP3A4MAPK1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0420356-B1 | Control of isomer distribution in a chlorination process | DOWELANCO (US) | 1995-03-01 | — | — | EP | claimed |
| EP-0420356-A2 | Control of isomer distribution in a chlorination process | DOWELANCO (US) | 1991-04-03 | — | — | EP | claimed |
| US-4939263-A | Control of isomer distribution in a chlorination process | THE DOW CHEMICAL COMPANY (US) | 1990-07-03 | — | — | US | claimed |
| EP-0228643-A2 | Removal of ferric chloride from halopyridines | THE DOW CHEMICAL COMPANY (US) | 1987-07-15 | — | — | EP | claimed |
| US-4649201-A | SOLVENT EXTRACTION, ALKYLENE GLYCOL | THE DOW CHEMICAL COMPANY (US) | 1987-03-10 | — | — | US | claimed |
| CN-116715387-A | Production process of herbicide clopyralid | 安徽海顺化工有限公司 | 2023-09-08 | — | — | CN | disclosed |
| CN-113912533-B | Method for preparing 3, 6-dichloropicolinic acid | 西安凯立新材料股份有限公司 | 2023-06-20 | — | — | CN | disclosed |
| CN-113912533-A | Method for preparing 3, 6-dichloropicolinic acid | 西安凯立新材料股份有限公司 | 2022-01-11 | — | — | CN | disclosed |
| CN-106316932-A | Method for preparing 2,3-dichloro-5-trichloromethylpyridine from DCTF distillation and rapid-steaming residues | 盐城工学院 | 2017-01-11 | — | — | CN | disclosed |
| CN-105884679-A | Method for preparing 5, 6-dichloro-3-hydroxymethylpyridine-2-phenol from DCTF rectification and short-steaming residues | 江苏天宇检测技术有限公司 | 2016-08-24 | — | — | CN | disclosed |
| WO-2015151116-A2 | PROCESS FOR PRODUCING 2-FLUORO-6-(TRIFLUOROMETHYL)PYRIDINE COMPOUNDS | JUBILANT LIFE SCIENCES LIMITED (IN) | 2015-10-08 | — | — | WO | disclosed |
| US-20100065416-A1 | 6-CHLORO-2-TRICHLOROMETHYL PYRIDINE PREPARATION METHOD | ZHEJIANG AOFUTUO CHEMISTRY INDUSTRIAL CO. (CN) | 2010-03-18 | — | — | US | disclosed |
| EP-0023077-B1 | ELECTROLYTIC PRODUCTION OF CERTAIN TRICHLOROPICOLINIC ACIDS AND/OR 3,6-DICHLOROPICOLINIC ACID | THE DOW CHEMICAL COMPANY (US) | 1984-06-20 | — | — | EP | disclosed |
| US-4334074-A | BY ACIDIFICATION WITH HYDROGEN CHLORIDE IN THE PRESENCE OF A FLOCCULANT | THE DOW CHEMICAL COMPANY (US) | 1982-06-08 | — | — | US | disclosed |
| US-4256894-A | REACTING LIQUID CHLORO-SUBSTITUTED (TRICHLOROMETHYL) PYRIDINE WITH CHLORINE IN THE PRESENCE OF A LEWIS ACID CATALYST | THE DOW CHEMICAL COMPANY (US) | 1981-03-17 | — | — | US | disclosed |
| EP-0023077-A2 | Electrolytic production of certain trichloropicolinic acids and/or 3,6-dichloropicolinic acid | THE DOW CHEMICAL COMPANY (US) | 1981-01-28 | — | — | EP | disclosed |
| US-4217185-A | Electrolytic production of certain trichloropicolinic acids and/or 3,6-dichloropicolinic acid | THE DOW CHEMICAL COMPANY (US) | 1980-08-12 | — | — | US | disclosed |
| EP-0005064-A1 | Process for preparing 2,3,5,6-tetrachloropyridine | THE DOW CHEMICAL COMPANY (US) | 1979-10-31 | — | — | EP | disclosed |
| US-4172203-A | FROM HYDRAZINO ADDUCTS OF TRICHLOROMETHYLPYRIDINE | THE DOW CHEMICAL COMPANY (US) | 1979-10-23 | — | — | US | disclosed |
| US-4087431-A | Preparation of 3,6-dichloropicolinic acid | THE DOW CHEMICAL COMPANY (US) | 1978-05-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100065416-A1 | 6-CHLORO-2-TRICHLOROMETHYL PYRIDINE PREPARATION METHOD | CBX6, CBX7, ABL1 | TSHR 3314/4885CYP3A4 517/4885CRHBP 4368/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.