Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30872394 | 0.79 | GLP1R (0.41) | CYP3A4ALDH1A1 | |
| SCHEMBL19024344 | 0.76 | GLP1R (0.35) | — | |
| SCHEMBL5946432 | 0.69 | CYP3A4 (0.40) | CYP3A4TSHRALDH1A1 | |
| SCHEMBL3153988 | 0.68 | TSHR (0.43) | CYP3A4TSHR | |
| SCHEMBL10457878 | 0.67 | HSD17B10 (0.46) | CYP3A4TSHRALDH1A1 | |
| SCHEMBL10933081 | 0.67 | TSHR (0.32) | CYP3A4TSHR | |
| SCHEMBL7111689 | 0.65 | ALDH1A1 (0.37) | CYP3A4TSHRALDH1A1 | |
| SCHEMBL28113759 | 0.65 | CYP3A4 (0.36) | CYP3A4TSHRALDH1A1 | |
| SCHEMBL9720940 | 0.64 | TSHR (0.40) | CYP3A4TSHR | |
| SCHEMBL10744062 | 0.64 | CYP3A4 (0.37) | CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4723019-A | CHLORINATION AND DISTILLATION | THE DOW CHEMICAL COMPANY (US) | 1988-02-02 | — | — | US | disclosed |
| US-4497697-A | REDUCTION OF TETRACHLOROPICOLINIC ACID IN A BASIC SOLUTION | THE DOW CHEMICAL COMPANY (US) | 1985-02-05 | — | — | US | disclosed |
| US-4227001-A | LEWIS ACID CATALYST | THE DOW CHEMICAL COMPANY (US) | 1980-10-07 | — | — | US | disclosed |
| EP-0007160-A1 | Preparation of polychlorinated pyridines from 2,4-dichloro-6-(trichloromethyl)pyridine | THE DOW CHEMICAL COMPANY (US) | 1980-01-23 | — | — | EP | disclosed |