SCHEMBL3153994

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3141272	0.87	F10 (0.43)	NNMTSMN1; SMN2HDAC1GABRPGABRD
	SCHEMBL3154818	0.86	NAMPT (0.55)	HDAC1GABRPGABRDGABRA1GABRB1
	SCHEMBL3139636	0.85	GABRP (0.40)	NNMTSMN1; SMN2HDAC1GABRPGABRD
	SCHEMBL3144601	0.83	GABRP (0.39)	SMN1; SMN2HDAC1GABRPGABRDGABRA1
	SCHEMBL3154969	0.82	NAMPT (0.39)	NNMTSMN1; SMN2HDAC1GABRPGABRD
	SCHEMBL3139983	0.82	HDAC1 (0.39)	HDAC1GABRPGABRDGABRA1GABRB1
	SCHEMBL3140045	0.81	NAMPT (0.43)	NNMTSMN1; SMN2HDAC1GABRPGABRD
	SCHEMBL3140763	0.80	TSHR (0.44)	SMN1; SMN2HDAC1GABRPGABRDGABRA1
	SCHEMBL3149644	0.80	NAMPT (0.44)	HDAC1GABRPGABRDGABRA1GABRB1
	SCHEMBL3153720	0.78	F2 (0.38)	HDAC1GABRPGABRDGABRA1GABRB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.