Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | PYGL | P06737 | 11/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | CCR2 | P41597 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL315402 | 1.00 | ALDH1A1 (0.58) | ALDH1A1PYGLHPGDLMNASMN1; SMN2 | |
| Iodide SCHEMBL17555180 | 0.99 | ALDH1A1 (0.57) | ALDH1A1PYGLHPGDLMNASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL2905992 | 0.99 | ALDH1A1 (0.57) | ALDH1A1PYGLHPGDLMNASMN1; SMN2 | |
| Iodide SCHEMBL17555178 | 0.99 | ALDH1A1 (0.57) | ALDH1A1PYGLHPGDLMNASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL2905994 | 0.99 | ALDH1A1 (0.57) | ALDH1A1PYGLHPGDLMNASMN1; SMN2 | |
| SCHEMBL13148204 | 0.89 | ALDH1A1 (0.60) | ALDH1A1PYGLHPGDLMNASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL2899956 | 0.88 | ALDH1A1 (0.59) | ALDH1A1PYGLHPGDLMNASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL2899954 | 0.88 | ALDH1A1 (0.59) | ALDH1A1PYGLHPGDLMNASMN1; SMN2 | |
| Iodide SCHEMBL17555285 | 0.88 | ALDH1A1 (0.59) | ALDH1A1PYGLHPGDLMNASMN1; SMN2 | |
| SCHEMBL2696192 | 0.88 | CCR2 (0.64) | ALDH1A1PYGLLMNASMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8168829-B2 | Synthesis of quaternary salt compounds | JANSSEN PHARMACEUTICA N.V. (BE) | 2012-05-01 | — | — | US | disclosed |
| US-8093428-B2 | Synthesis of quaternary salt compounds | JANSSEN PHARMACEUTICA N.V. (BE) | 2012-01-10 | — | — | US | disclosed |
| US-20090112003-A1 | SYNTHESIS OF QUATERNARY SALT COMPOUNDS | JANSSEN PHARMACEUTICA N.V. (BE) | 2009-04-30 | — | — | US | disclosed |
| US-20090112004-A1 | SYNTHESIS OF QUATERNARY SALT COMPOUNDS | JANSSEN PHARMACEUTICA N.V. (BE) | 2009-04-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090112003-A1 | SYNTHESIS OF QUATERNARY SALT COMPOUNDS | CCR2, CCR1, CCL11 | ALDH1A1 1764/4885PYGL 4883/4885HPGD 1716/4885 |
| US-20090112004-A1 | SYNTHESIS OF QUATERNARY SALT COMPOUNDS | CCR2, CCR1, CCL11 | ALDH1A1 1764/4885PYGL 4883/4885HPGD 1716/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.