Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.68 |
| ▸ | ANPEP | P15144 | 2/20 | 0.58 |
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | GMNN | O75496 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.40 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | SCN1A | P35498 | 1/20 | 0.38 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.38 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27980382 | 0.81 | KDM4E (1.00) | KDM4EANPEPERAP2SMN1; SMN2HTT | |
| SCHEMBL3393821 | 0.81 | KDM4E (0.74) | KDM4EANPEPERAP2SMN1; SMN2HTT | |
| SCHEMBL30777623 | 0.79 | KDM4E (0.71) | KDM4EANPEPERAP2SMN1; SMN2HTT | |
| SCHEMBL9516706 | 0.78 | KDM4E (0.76) | KDM4EANPEPERAP2SMN1; SMN2HTT | |
| SCHEMBL24715431 | 0.77 | KDM4E (0.68) | KDM4EANPEPERAP2SMN1; SMN2HTT | |
| SCHEMBL4611607 | 0.77 | KDM4E (0.68) | KDM4EANPEPERAP2SMN1; SMN2HTT | |
| SCHEMBL1274004 | 0.77 | KDM4E (0.56) | KDM4EANPEPERAP2SMN1; SMN2HTT | |
| SCHEMBL1443685 | 0.77 | KDM4E (0.56) | KDM4EANPEPERAP2SMN1; SMN2HTT | |
| SCHEMBL16822346 | 0.77 | KDM4E (0.68) | KDM4EANPEPERAP2SMN1; SMN2HTT | |
| SCHEMBL23132214 | 0.77 | KDM4E (0.68) | KDM4EANPEPERAP2SMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112962192-B | Cool elastic jean fabric and preparation method thereof | 广东明丰纺织品有限公司 | 2023-01-10 | — | — | CN | disclosed |
| CN-112962192-A | Cool elastic jean fabric and preparation method thereof | 广东明丰纺织品有限公司 | 2021-06-15 | — | — | CN | disclosed |
| EP-1449529-B1 | Protein Kinase C Inhibitors | LILLY CO ELI (US) | 2010-01-27 | — | — | EP | disclosed |
| EP-1449529-A1 | Protein Kinase C Inhibitors | ELI LILLY AND COMPANY (US) | 2004-08-25 | — | — | EP | disclosed |
| EP-0574174-B1 | Angiotensin II antagonists | LILLY CO ELI (US) | 2003-08-13 | — | — | EP | disclosed |
| US-5693633-A | Angiotensin II antagonists | ELI LILLY AND COMPANY (US) | 1997-12-02 | — | — | US | disclosed |
| US-5672618-A | TREATING DIABETIC COMPLICATIONS | ELI LILLY AND COMPANY (US) | 1997-09-30 | — | — | US | disclosed |
| US-5668152-A | BIS/INDOLE/-SUBSTITUTED MALEIMIDES, ANTIDIABETIC AGENTS | ELI LILLY AND COMPANY (US) | 1997-09-16 | — | — | US | disclosed |
| US-5661173-A | ADMINISTERING AN ENZYME INHIBITOR TREATING DIABETES | ELI LILLY AND COMPANY (US) | 1997-08-26 | — | — | US | disclosed |
| US-5612360-A | AROMATIC N-HETEROCYCLIC COMPOUNDS AS HYPOTENSIVE AGENTS WITH ACID GROUPS, SULFONYLCARBOXAMIDES OR TETRAZOLE GROUPS | ELI LILLY AND COMPANY (US) | 1997-03-18 | — | — | US | disclosed |
| US-5569768-A | USEFUL IN TREATING HYPERTENSION, CONGESTIVE HEART FAILURE, GLAUCOMA AND RENAL INSUFFICIENCY | ELI LILLY AND COMPANY (US) | 1996-10-29 | — | — | US | disclosed |
| US-5556981-A | Angiotensin II antagonist intermediates | ELI LILLY AND COMPANY (US) | 1996-09-17 | — | — | US | disclosed |
| US-5545636-A | TREATING DIABETES MELLITUS | ELI LILLY AND COMPANY (US) | 1996-08-13 | — | — | US | disclosed |
| US-5484780-A | CARDIOVASCULAR, HYPOTENSIVE | ELI LILLY AND COMPANY (US) | 1996-01-16 | — | — | US | disclosed |
| US-5401851-A | Preparation of proline derivatives | ELI LILLY AND COMPANY (US) | 1995-03-28 | — | — | US | disclosed |
| EP-0574174-A2 | Angiotensin II antagonists | ELI LILLY AND COMPANY (US) | 1993-12-15 | — | — | EP | disclosed |
| EP-0573271-A1 | Angiotensin II antagonists | ELI LILLY AND COMPANY (US) | 1993-12-08 | — | — | EP | disclosed |
| US-4880692-A | RUNNING DURABILITY; REDUCED NUMBER OF DROP-OUTS; AMINE MODIFIED VINYL ACETATE-VINYL CHLORIDE COPOLYMER BINDER | FUJI PHOTO FILM CO., LTD. (JP) | 1989-11-14 | — | — | US | disclosed |
| US-4880693-A | NONMAGNETIC SUPPORT; DURABILITY AND IMPROVED DROPOUT; AMINE MODIFIED VINYL ACETATE-VINYL CHLORIDE COPOLYMER SUPPORT | FUJI PHOTO FILM CO., LTD. (JP) | 1989-11-14 | — | — | US | disclosed |
| EP-0063817-A1 | Metallic base paint | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1982-11-03 | — | — | EP | disclosed |