SCHEMBL4611607

SCHEMBL4611607

[CH2]C(O)CNC1CCCCC1

nearest known ligand 0.68

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.68
SMN1; SMN2 Q16637 2/20 0.53
HTT P42858 1/20 0.53
ANPEP P15144 2/20 0.48
ERAP2 Q6P179 2/20 0.48
SLC2A1 P11166 1/20 0.41
PABPC1 P11940 1/20 0.38
LMNA P02545 1/20 0.38
CYP1A2 P05177 1/20 0.38
CYP2D6 P10635 1/20 0.38
SCN1A P35498 1/20 0.38
SCN2A Q99250 1/20 0.38
SCN3A Q9NY46 1/20 0.38
DPP7 Q9UHL4 1/20 0.37
TP53 P04637 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9124679 0.98 KDM4E (0.64) KDM4ESMN1; SMN2HTTANPEPERAP2
SCHEMBL1828528 0.88
SCHEMBL3393821 0.81 KDM4E (0.74) KDM4ESMN1; SMN2HTTANPEPERAP2
SCHEMBL27980382 0.81 KDM4E (1.00) KDM4ESMN1; SMN2HTTANPEPERAP2
SCHEMBL30777623 0.79 KDM4E (0.71) KDM4ESMN1; SMN2HTTANPEPERAP2
SCHEMBL5930050 0.78 KDM4E (0.42) KDM4ESMN1; SMN2HTTANPEPERAP2
SCHEMBL24715431 0.77 KDM4E (0.68) KDM4ESMN1; SMN2HTTANPEPERAP2
SCHEMBL3154036 0.77 KDM4E (0.68) KDM4ESMN1; SMN2HTTANPEPERAP2
SCHEMBL6984920 0.77 KDM4E (0.68) KDM4ESMN1; SMN2HTTANPEPERAP2
SCHEMBL23132214 0.77 KDM4E (0.68) KDM4ESMN1; SMN2HTTANPEPERAP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0679945-B1 Processing of a silver halide photgraphic with a peroxide bleach composition EASTMAN KODAK CO (US) 1998-08-19 EP claimed
EP-0679945-A2 Hydrogen peroxide bleach composition for use with silver halide photographic elements EASTMAN KODAK COMPANY (US) 1995-11-02 EP claimed
CN-100516075-C Method for producing silicon compound having amino group WACKER CHEMIE GMBH (DE) 2009-07-22 CN disclosed
EP-1865016-B1 Organosilicon compounds comprising cyclodextrin radicals WACKER CHEMIE AG (DE) 2008-11-26 EP disclosed
EP-1530607-B1 ORGANOSILICON COMPOUNDS COMPRISING CYCLODEXTRIN RADICALS WACKER CHEMIE AG (DE) 2008-10-29 EP disclosed
EP-1865016-A1 Organosilicon compounds comprising cyclodextrin radicals Wacker Chemie AG (DE) 2007-12-12 EP disclosed
US-7235186-B2 Organosilicon compounds comprising cyclodextrin radicals WACKER CHEMIE AG (DE) 2007-06-26 US disclosed
CN-1878780-A Method for producing silicon compound having amino group WACKER CHEMIE GMBH (DE) 2006-12-13 CN disclosed
US-20060009592-A1 Organosilicon compounds comprising cyclodextrin radicals WACKER-CHEMIE GMBH (DE) 2006-01-12 US disclosed
EP-0679945-B1 Processing of a silver halide photgraphic with a peroxide bleach composition EASTMAN KODAK CO (US) 1998-08-19 EP disclosed
US-5641615-A USING ACIDIC AQUEOUS SOLUTION OF HYDROGEN PEROXIDE OR PEROXIDE PRECURSOR CONTAINING SULFONIC ACID COMPOUND, WHICH IS FREE OF REHALOGENATING AGENTS AND MULTIVALENT METAL ION COMPLEXES EASTMAN KODAK COMPANY (US) 1997-06-24 US disclosed
US-5476848-A Antihistamines SANKYO COMPANY, LIMITED (JP) 1995-12-19 US disclosed
EP-0679945-A2 Hydrogen peroxide bleach composition for use with silver halide photographic elements EASTMAN KODAK COMPANY (US) 1995-11-02 EP disclosed
US-5461051-A Tetracyclic compounds having anti-allergic and anti-asthmatic activities and their use SANKYO COMPANY, LIMITED (JP) 1995-10-24 US disclosed
US-5362725-A Antiallergens, antiasthmatic SANKYO COMPANY, LIMITED (JP) 1994-11-08 US disclosed
EP-0505014-A2 Novel tetracyclic compounds having anti-allergic and anti-asthmatic activities, their preparation and use Sankyo Company Limited (JP) 1992-09-23 EP disclosed
EP-0421823-A2 Novel tetracyclic compounds having anti-allergic and anti-asthmatic activities, their preparation and use Sankyo Company Limited (JP) 1991-04-10 EP disclosed