SCHEMBL9516706

SCHEMBL9516706

NCC(O)CNC1CCCCC1

nearest known ligand 0.76

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.76
SMN1; SMN2 Q16637 3/20 0.59
HTT P42858 1/20 0.59
ANPEP P15144 2/20 0.50
ERAP2 Q6P179 2/20 0.50
TP53 P04637 1/20 0.48
LMNA P02545 2/20 0.47
GMNN O75496 1/20 0.47
MAPT P10636 1/20 0.47
BLM P54132 1/20 0.47
PMP22 Q01453 1/20 0.47
SLC2A1 P11166 1/20 0.46
EPHX1 P07099 1/20 0.41
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5256777 0.89
SCHEMBL27980382 0.87 KDM4E (1.00) KDM4ESMN1; SMN2HTTANPEPERAP2
SCHEMBL16822348 0.81 KDM4E (0.79) KDM4ESMN1; SMN2HTTANPEPERAP2
SCHEMBL3535515 0.81 KDM4E (0.79) KDM4ESMN1; SMN2HTTANPEPERAP2
SCHEMBL3539236 0.79 KDM4E (0.76) KDM4ESMN1; SMN2HTTANPEPERAP2
SCHEMBL18263370 0.79 KDM4E (0.57) KDM4ESMN1; SMN2HTTANPEPERAP2
SCHEMBL9476242 0.79 KDM4E (0.76) KDM4ESMN1; SMN2HTTANPEPERAP2
SCHEMBL6644034 0.78 KDM4E (0.75) KDM4ESMN1; SMN2HTTANPEPERAP2
SCHEMBL3154036 0.78 KDM4E (0.68) KDM4ESMN1; SMN2HTTANPEPERAP2
SCHEMBL3393821 0.78 KDM4E (0.74) KDM4ESMN1; SMN2HTTANPEPERAP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3154937-B1 CHLORINE-RESISTANT POLYETHYLENE COMPOUND AND ARTICLES MADE THEREFROM FINA TECHNOLOGY (US) 2024-05-22 EP claimed
US-10584823-B2 Chlorine-resistant polyethylene compound and articles made therefrom FINA TECHNOLOGY, INC. (US) 2020-03-10 US claimed
EP-3154937-A1 CHLORINE-RESISTANT POLYETHYLENE COMPOUND AND ARTICLES MADE THEREFROM Fina Technology, Inc. (US) 2017-04-19 EP claimed
US-20170089503-A1 Chlorine-resistant Polyethylene Compound and Articles Made Therefrom TOTAL AMERICAN SERVICES, INC. 2017-03-30 US claimed
WO-2015191721-A1 CHLORINE-RESISTANT POLYETHYLENE COMPOUND AND ARTICLES MADE THEREFROM FINA TECHNOLOGY, INC. (US) 2015-12-17 WO claimed
US-4217237-A Process for removing carbon dioxide containing acidic gases from gaseous mixtures using a basic salt activated with a hindered amine EXXON RESEARCH & ENGINEERING CO. (US) 1980-08-12 US claimed
US-4112050-A Process for removing carbon dioxide containing acidic gases from gaseous mixtures using a basic salt activated with a hindered amine EXXON RESEARCH & ENGINEERING CO. (US) 1978-09-05 US claimed
EP-3154937-B1 CHLORINE-RESISTANT POLYETHYLENE COMPOUND AND ARTICLES MADE THEREFROM FINA TECHNOLOGY (US) 2024-05-22 EP disclosed
US-10584823-B2 Chlorine-resistant polyethylene compound and articles made therefrom FINA TECHNOLOGY, INC. (US) 2020-03-10 US disclosed
US-20180162862-A1 INHIBITORS OF BACTERIAL GLYCOSYL TRANSFERASES PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2018-06-14 US disclosed
EP-3303338-A1 INHIBITORS OF BACTERIAL GLYCOSYL TRANSFERASES President and Fellows of Harvard College (US) 2018-04-11 EP disclosed
EP-3154937-A1 CHLORINE-RESISTANT POLYETHYLENE COMPOUND AND ARTICLES MADE THEREFROM Fina Technology, Inc. (US) 2017-04-19 EP disclosed
US-20170089503-A1 Chlorine-resistant Polyethylene Compound and Articles Made Therefrom TOTAL AMERICAN SERVICES, INC. 2017-03-30 US disclosed
WO-2016191658-A1 INHIBITORS OF BACTERIAL GLYCOSYL TRANSFERASES PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2016-12-01 WO disclosed
WO-2015191721-A1 CHLORINE-RESISTANT POLYETHYLENE COMPOUND AND ARTICLES MADE THEREFROM FINA TECHNOLOGY, INC. (US) 2015-12-17 WO disclosed
EP-0544515-A1 Process and apparatus for removing acid gas from a gas mixture EXXON CHEMICAL PATENTS INC. (US) 1993-06-02 EP disclosed
US-4217238-A BASIC SALT, SCRUBBING EXXON RESEARCH & ENGINEERING CO. (US) 1980-08-12 US disclosed
US-4112050-A Process for removing carbon dioxide containing acidic gases from gaseous mixtures using a basic salt activated with a hindered amine EXXON RESEARCH & ENGINEERING CO. (US) 1978-09-05 US disclosed
US-4094957-A CARBON DIOXIDE EXXON RESEARCH & ENGINEERING CO. (US) 1978-06-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180162862-A1 INHIBITORS OF BACTERIAL GLYCOSYL TRANSFERASES SI, UGGT1, ALPI KDM4E 2392/4885SMN1; SMN2 4557/4885HTT 3721/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.