Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | GSK3A | P49840 | 1/20 | 0.48 |
| ▸ | GSK3B | P49841 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | MGAM | O43451 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | SI | P14410 | 1/20 | 0.44 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.43 |
| ▸ | PIN4 | Q9Y237 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ELANE | P08246 | 1/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL333146 | 0.77 | POLB (0.54) | HSD17B10PKMATMGSK3AGSK3B | |
| SCHEMBL16586833 | 0.75 | NPSR1 (0.47) | HSD17B10PKMGAASMN1; SMN2ALDH1A1 | |
| SCHEMBL1093819 | 0.75 | GSK3A (0.44) | HSD17B10GSK3AGSK3BMAPK1MGAM | |
| SCHEMBL28604654 | 0.72 | HSD17B10 (0.54) | HSD17B10PKMATMGSK3AGSK3B | |
| SCHEMBL2823777 | 0.72 | MAPK1 (0.51) | HSD17B10GSK3AGSK3BMAPK1GAA | |
| SCHEMBL6962065 | 0.72 | ALDH1A1 (0.57) | HSD17B10PKMATMMAPK1GAA | |
| SCHEMBL22824510 | 0.71 | TDP1 (0.41) | — | |
| SCHEMBL5795696 | 0.71 | ALDH1A1 (0.42) | HSD17B10GSK3AGSK3BMGAMGAA | |
| SCHEMBL11110430 | 0.71 | GSK3A (0.48) | HSD17B10PKMATMGSK3AGSK3B | |
| SCHEMBL7206290 | 0.71 | MAPK1 (0.49) | HSD17B10GSK3AGSK3BMAPK1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025051214-A1 | AROMATIC HETEROCYCLIC COMPOUND AND PREPARATION METHOD THEREFOR | 上海翊石医药科技有限公司 | 2025-03-13 | — | — | WO | disclosed |
| US-10301289-B2 | Method for the preparation of triazole compounds | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2019-05-28 | — | — | US | disclosed |
| US-20180282331-A1 | 7-Oxo -6-(sulfooxy)- 1,6-diazabicyclo [3.2.1] octane containing compounds and their use in treatment of bacterial infections (changed by PCT to: 7-OXO -6-(SULFOOXY)- 1,6-DIAZABICYCLO [3.2.1] OCTANE CONTAINING COMPOUNDS AND THEIR USE IN TREATMENT OF BACTERIAL INFECTIONS | WOCKHARDT LIMITED (IN) | 2018-10-04 | — | — | US | disclosed |
| WO-2017081615-A1 | 7-OXO -6-(SULFOOXY)- 1,6-DIAZABICYCLO [3.2.1] OCTANE CONTAINING COMPOUNDS AND THEIR USE IN TREATMENT OF BACTERIAL INFECTIONS | WOCKHARDT LIMITED (IN) | 2017-05-18 | — | — | WO | disclosed |
| US-20150087827-A1 | METHOD FOR THE PREPARATION OF TRIAZOLE COMPOUNDS | BAYER PHARMA AKTIENGESELLSCAFT (DE) | 2015-03-26 | — | — | US | disclosed |
| US-20150087827-A1 | METHOD FOR THE PREPARATION OF TRIAZOLE COMPOUNDS | BAYER PHARMA AKTIENGESELLSCAFT (DE) | 2015-03-26 | — | — | US | disclosed |
| US-8093400-B2 | Compounds useful in therapy | PFIZER INC. (US) | 2012-01-10 | — | — | US | disclosed |
| US-8093400-B2 | Compounds useful in therapy | PFIZER INC. (US) | 2012-01-10 | — | — | US | disclosed |
| US-8093400-B2 | Compounds useful in therapy | PFIZER INC. (US) | 2012-01-10 | — | — | US | disclosed |
| US-20100317652-A1 | Compounds Useful In Therapy | PFIZER INC | 2010-12-16 | — | — | US | disclosed |
| WO-2005063754-A1 | TRIAZOLE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | PFIZER LIMITED (GB) | 2005-07-14 | — | — | WO | disclosed |
| WO-2005000841-A1 | PREPARATION OF N2-ALKYLATED 1,2,3-TRIAZOLES | WARNER-LAMBERT COMPANY LLC (US) | 2005-01-06 | — | — | WO | disclosed |
| US-20040266848-A1 | Preparation of N2-alkylated 1,2,3-triazoles | HADD MARK ALLEN (US) | 2004-12-30 | — | — | US | disclosed |
| EP-1490060-A1 | ANTIDIABETIC AGENTS | WARNER-LAMBERT COMPANY LLC (US) | 2004-12-29 | — | — | EP | disclosed |
| CN-1558897-A | oral antidiabetic agent | ����-�����ع�˾ | 2004-12-29 | — | — | CN | disclosed |
| US-6696474-B2 | SUCH AS 8-(5-METHYL-2-PHENYL-OXAZOL-4-YL)-2-PYRROL-1-YL-OCT-4-YNOIC ACID; NONINSULIN DEPENDENT DIABETES MELLITUS | WARNER LAMBERT CO. LLC. | 2004-02-24 | — | — | US | disclosed |
| US-20030220381-A1 | ANTIDIABETIC AGENTS | WARNER-LAMBERT COMPANY, LLC | 2003-11-27 | — | — | US | disclosed |
| WO-2003082276-A1 | ANTIDIABETIC AGENTS | WARNER-LAMBERT COMPANY LLC (US) | 2003-10-09 | — | — | WO | disclosed |
| CN-1031133-C | Pyrazolotriazole derivatives | YAMANOUCHI PHARMA CO LTD (JP) | 1996-02-28 | — | — | CN | disclosed |
| CN-1069978-A | Pyrazolotriazole derivatives | YAMANOUCHI PHARMA CO LTD (JP) | 1993-03-17 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040266848-A1 | Preparation of N2-alkylated 1,2,3-triazoles | PPARA, PPARG, PPARD | HSD17B10 1909/4885PKM 1227/4885ATM 2408/4885 |
| US-20030220381-A1 | ANTIDIABETIC AGENTS | GPR119, GCKR, GLP1R | HSD17B10 897/4885PKM 226/4885ATM 3074/4885 |
| US-10301289-B2 | Method for the preparation of triazole compounds | CYP4B1, BRI3BP, BRD4 | HSD17B10 3597/4885PKM 172/4885ATM 2429/4885 |
| US-20150087827-A1 | METHOD FOR THE PREPARATION OF TRIAZOLE COMPOUNDS | CYP4B1, BRI3BP, BRD4 | HSD17B10 3597/4885PKM 172/4885ATM 2429/4885 |
| US-20180282331-A1 | 7-Oxo -6-(sulfooxy)- 1,6-diazabicyclo [3.2.1] octane containing compounds and their use in treatment of bacterial infections (changed by PCT to: 7-OXO -6-(SULFOOXY)- 1,6-DIAZABICYCLO [3.2.1] OCTANE CONTAINING COMPOUNDS AND THEIR USE IN TREATMENT OF BACTERIAL INFECTIONS | TST, THPO, STS | HSD17B10 1728/4885PKM 3431/4885ATM 2354/4885 |
| US-20100317652-A1 | Compounds Useful In Therapy | AVPR1A, AVPR1B, AVPR2 | HSD17B10 2776/4885PKM 1270/4885ATM 4532/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.