Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.63 |
| ▸ | DRD2 | P14416 | 4/20 | 0.62 |
| ▸ | TBXA2R | P21731 | 4/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.62 |
| ▸ | NPC1 | O15118 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | BLM | P54132 | 1/20 | 0.57 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | HTR7 | P34969 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31542084 | 0.90 | ALDH1A1 (0.78) | POLBALDH1A1NPC1RAB9AKMT2A | |
| SCHEMBL31542064 | 0.87 | ALDH1A1 (0.61) | ALDH1A1NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL31542077 | 0.86 | ALDH1A1 (0.57) | POLBDRD2TBXA2RALDH1A1NPC1 | |
| SCHEMBL31542083 | 0.82 | POLB (0.56) | POLBDRD2TBXA2RALDH1A1NPC1 | |
| SCHEMBL4958333 | 0.80 | LMNA (0.73) | POLBALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL31542069 | 0.80 | ALDH1A1 (0.75) | ALDH1A1NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL31542055 | 0.78 | NPC1 (0.70) | ALDH1A1NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL7018781 | 0.78 | ALDH1A1 (0.60) | ALDH1A1NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL447996 | 0.77 | HTR7 (0.59) | ALDH1A1NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL31542078 | 0.77 | POLB (0.51) | POLBDRD2TBXA2RALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4622964-A1 | QUINAZOLINONE DERIVATIVES FOR HDAC INHIBITION | Gilva Therapeutics Co., Ltd. (TW) | 2025-10-01 | — | — | EP | disclosed |
| WO-2025085669-A1 | QUINAZOLINONE DERIVATIVES FOR HDAC INHIBITION | GILVA THERAPEUTICS CO., LTD. (CN) | 2025-04-24 | — | — | WO | disclosed |