Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | FDPS | P14324 | 2/20 | 0.32 |
| ▸ | PPARD | Q03181 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18486439 | 0.67 | LMNA (0.39) | TSHRFDPSPPARD | |
| SCHEMBL98484 | 0.67 | LMNA (0.39) | FDPS | |
| SCHEMBL13186023 | 0.67 | LMNA (0.39) | TSHRALDH1A1FDPSPPARD | |
| SCHEMBL18486646 | 0.65 | FDPS (0.36) | TSHRFDPSPPARD | |
| SCHEMBL29155304 | 0.65 | FDPS (0.36) | FDPS | |
| SCHEMBL8878747 | 0.64 | FDPS (0.31) | TSHRFDPS | |
| SCHEMBL11151927 | 0.64 | FDPS (0.34) | FDPS | |
| SCHEMBL27783191 | 0.64 | FDPS (0.40) | FDPS | |
| SCHEMBL5887949 | 0.63 | — | — | |
| SCHEMBL4835941 | 0.62 | FDPS (0.33) | FDPSPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116888101-A | Substituted isoxazoline derivatives | 巴斯夫欧洲公司 | 2023-10-13 | — | — | CN | disclosed |
| US-8076325-B2 | 1,2,4,5-tetrahydro-3H-benzazepine compounds, a process for their preparation and pharmaceutical compositions containing them | LES LABORATOIRES SERVIER (FR) | 2011-12-13 | — | — | US | disclosed |
| EP-2036892-B1 | 1,2,4,5-tetrahydro-3H-benzazepine derivatives, process for their preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2010-03-10 | — | — | EP | disclosed |
| WO-2009066041-A2 | DERIVATIVES OF 1,2,4,5-TETRAHYDRO-3H-BENZAZEPINES, PREPARATION METHOD THEREFOR AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | LES LABORATOIRES SERVIER (FR) | 2009-05-28 | — | — | WO | disclosed |
| EP-2036892-A1 | 1,2,4,5-tetrahydro-3H-benzazepine derivatives, process for their preparation and pharmaceutical compositions containing them | Les Laboratoires Servier (FR) | 2009-03-18 | — | — | EP | disclosed |
| US-20090069296-A1 | 1,2,4,5-Tetrahydro-3H-benzazepine compounds, a process for their preparation and pharmaceutical compositions containing them | LES LABORATOIRES SERVIER (FR) | 2009-03-12 | — | — | US | disclosed |
| US-4273713-A | ANTIULCER AND ANTISECRETORY AGENTS | STERLING DRUG INC. (US) | 1981-06-16 | — | — | US | disclosed |
| US-4259338-A | Benzofuranyl-tetrahydropyridines and -piperidines, their acid addition salts and antidepressant preparations thereof | CIBA-GEIGY CORPORATION (US) | 1981-03-31 | — | — | US | disclosed |
| US-4239687-A | 4-CARBOXAMIDES, 4-THIOCARBOXAMIDES, 4-NITRILES, ANTISECRETORY, ANTIULCER | STERLING DRUG INC. (US) | 1980-12-16 | — | — | US | disclosed |
| US-4140854-A | ANTISECRETORY, ANTIULCER | STERLING DRUG INC. (US) | 1979-02-20 | — | — | US | disclosed |
| US-4098797-A | ANTISECRETORY, ANTIULCER AGENTS | STERLING DRUG INC. (US) | 1978-07-04 | — | — | US | disclosed |
| US-4008250-A | ANTISECRETORY, ANTIULCER | STERLING DRUG INC. (US) | 1977-02-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090069296-A1 | 1,2,4,5-Tetrahydro-3H-benzazepine compounds, a process for their preparation and pharmaceutical compositions containing them | OXER1, NR1H3, OXSR1 | TSHR 268/4885ALDH1A1 1056/4885ACHE 2167/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.