Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 4/20 | 0.33 |
| ▸ | PPARD | Q03181 | 1/20 | 0.31 |
| ▸ | GGPS1 | O95749 | 2/20 | 0.30 |
| ▸ | PGK1 | P00558 | 1/20 | 0.30 |
| ▸ | PGK2 | P07205 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7829298 | 0.78 | ALDH1A1 (0.37) | — | |
| SCHEMBL2747154 | 0.78 | PTPN1 (0.33) | FDPS | |
| SCHEMBL4284951 | 0.78 | — | — | |
| SCHEMBL4157226 | 0.76 | LMNA (0.33) | FDPSPPARD | |
| SCHEMBL5697048 | 0.75 | LMNA (0.35) | FDPS | |
| SCHEMBL27617160 | 0.75 | DGAT1 (0.36) | — | |
| SCHEMBL4164631 | 0.72 | FDPS (0.33) | FDPSPPARD | |
| SCHEMBL18486439 | 0.69 | LMNA (0.39) | FDPSPPARDGGPS1 | |
| SCHEMBL13186023 | 0.69 | LMNA (0.39) | FDPSPPARDGGPS1 | |
| SCHEMBL5947964 | 0.67 | ALDH1A1 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118903088-A | Composition of fused tricyclic gamma-amino acid derivative and preparation thereof | 四川海思科制药有限公司 | 2024-11-08 | — | — | CN | disclosed |
| CN-112384494-B | Composition of fused tricyclic gamma-amino acid derivative and preparation thereof | 四川海思科制药有限公司 | 2024-08-06 | — | — | CN | disclosed |
| CN-111918859-B | Crystal forms of salts of fused tricyclic gamma-amino acid derivatives, preparation and use | 四川海思科制药有限公司 | 2023-06-30 | — | — | CN | disclosed |
| CN-114423734-A | Metadiamide insecticides | FMC公司 | 2022-04-29 | — | — | CN | disclosed |
| CN-108689942-A | Nitrogenous dicyclic compound and its preparation method and application | 广东东阳光药业有限公司 | 2018-10-23 | — | — | CN | disclosed |
| US-7368476-B2 | Hydroxamates as therapeutic agents | PHARMACYCLICS, INC. (US) | 2008-05-06 | — | — | US | disclosed |
| WO-2005097770-A1 | NOVEL HYDROXAMATES AS THERAPEUTIC AGENTS | PHARMACYCLICS, INC. (US) | 2005-10-20 | — | — | WO | disclosed |
| US-20050227976-A1 | Novel hydroxamates as therapeutic agents | AXYS PHARMACEUTICALS, INC. (US) | 2005-10-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050227976-A1 | Novel hydroxamates as therapeutic agents | HDAC1, HDAC5, HDAC10 | FDPS 2762/4885PPARD 1066/4885GGPS1 3589/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.