Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | DRD2 | P14416 | 2/20 | 0.55 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | TNKS | O95271 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31542057 | 0.86 | HDAC6 (0.60) | HDAC6HDAC8KMT2AACKR3ALDH1A1 | |
| SCHEMBL2881289 | 0.84 | DRD2 (0.68) | DRD2TBXA2RHDAC6NPC1RAB9A | |
| SCHEMBL31542078 | 0.83 | POLB (0.51) | POLBDRD2TBXA2RKMT2AMEN1 | |
| SCHEMBL31542077 | 0.82 | ALDH1A1 (0.57) | POLBDRD2TBXA2RKMT2AMEN1 | |
| SCHEMBL31542082 | 0.82 | POLB (0.63) | POLBDRD2TBXA2RKMT2AMEN1 | |
| SCHEMBL31542084 | 0.82 | ALDH1A1 (0.78) | POLBKMT2AMEN1ALDH1A1NPC1 | |
| SCHEMBL403865 | 0.77 | ALDH1A1 (0.48) | DRD2TBXA2RHDAC6HDAC8KMT2A | |
| SCHEMBL2883864 | 0.77 | DRD2 (0.71) | POLBDRD2TBXA2RKMT2AMEN1 | |
| SCHEMBL3518718 | 0.75 | KMT2A (0.67) | POLBKMT2AMEN1TNKSNPC1 | |
| SCHEMBL3969671 | 0.74 | KDM4E (0.61) | POLBKMT2AMEN1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4622964-A1 | QUINAZOLINONE DERIVATIVES FOR HDAC INHIBITION | Gilva Therapeutics Co., Ltd. (TW) | 2025-10-01 | — | — | EP | disclosed |
| WO-2025085669-A1 | QUINAZOLINONE DERIVATIVES FOR HDAC INHIBITION | GILVA THERAPEUTICS CO., LTD. (CN) | 2025-04-24 | — | — | WO | disclosed |