Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.44 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | FGB | P02675 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31544220 | 1.00 | ALOX15 (0.50) | ALOX15HSD17B10CRBNHTTLMNA | |
| SCHEMBL3591862 | 0.89 | ALOX15 (0.53) | ALOX15HSD17B10CRBNHTTLMNA | |
| SCHEMBL5098469 | 0.82 | ALOX15 (0.46) | ALOX15HSD17B10CRBNHTTLMNA | |
| SCHEMBL6747710 | 0.80 | ALDH1A1 (0.44) | LMNAALDH1A1HPGDMAPTMEN1 | |
| SCHEMBL17713638 | 0.80 | EPHX2 (0.39) | HPGDMAPTMEN1KMT2A | |
| SCHEMBL28919921 | 0.77 | ALOX5 (0.46) | ALOX15HSD17B10CRBNHTTLMNA | |
| SCHEMBL30874449 | 0.77 | ALOX5 (0.46) | ALOX15HSD17B10CRBNHTTLMNA | |
| SCHEMBL6219159 | 0.77 | EPHX2 (0.40) | ALDH1A1HPGDMAPT | |
| SCHEMBL22226780 | 0.77 | ALOX5 (0.46) | ALOX15HSD17B10CRBNHTTLMNA | |
| SCHEMBL7518140 | 0.77 | CRBN (0.50) | ALOX15HSD17B10CRBNHTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025098450-A1 | PRMT5 INHIBITOR AND PREPARATION METHOD THEREFOR | 北京泰德制药股份有限公司 | 2025-05-15 | — | — | WO | disclosed |