Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F11 | P03951 | 16/20 | 0.42 |
| ▸ | KLK1 | P06870 | 2/20 | 0.42 |
| ▸ | FLT3 | P36888 | 2/20 | 0.41 |
| ▸ | GSK3B | P49841 | 2/20 | 0.41 |
| ▸ | KLKB1 | P03952 | 13/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30995002 | 0.82 | FLT3 (0.46) | F11FLT3GSK3BKLKB1NOTUM | |
| SCHEMBL31252194 | 0.82 | F11 (0.45) | F11KLKB1CYP3A4 | |
| SCHEMBL31252350 | 0.79 | F11 (0.42) | F11KLK1KLKB1CYP3A4 | |
| SCHEMBL17302638 | 0.77 | NOTUM (0.43) | F11KLK1KLKB1CYP3A4NOTUM | |
| SCHEMBL16983100 | 0.77 | RXRA (0.42) | F11KLKB1CYP3A4NOTUM | |
| SCHEMBL30702184 | 0.77 | NOTUM (0.40) | F11KLK1KLKB1CYP3A4NOTUM | |
| SCHEMBL18797499 | 0.77 | NOTUM (0.40) | F11KLK1KLKB1CYP3A4NOTUM | |
| SCHEMBL16971450 | 0.75 | F11 (0.40) | F11KLK1KLKB1CYP3A4 | |
| SCHEMBL17661915 | 0.75 | NOTUM (0.41) | F11KLKB1CYP3A4NOTUM | |
| SCHEMBL22567236 | 0.74 | F11 (0.41) | F11KLK1KLKB1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119894901-A | Polysubstituted macrocyclic compound, and preparation method and application thereof | 深圳信立泰药业股份有限公司 | 2025-04-25 | — | — | CN | disclosed |