Cyclobendazole

Cyclobendazole

SCHEMBL31544741

COC(=O)Nc1nc2ccc(C(=O)C3CC3)cc2[nH]1

nearest known ligand 0.65

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 7/20 0.65
CYP1A2 P05177 6/20 0.65
HIF1A Q16665 5/20 0.65
ALDH1A1 P00352 3/20 0.65
KDR P35968 2/20 0.65
ABL1 P00519 2/20 0.65
CYP2C9 P11712 2/20 0.65
HTT P42858 2/20 0.65
ABCC4 O15439 1/20 0.65
USP2 O75604 1/20 0.65
MAPK1 P28482 4/20 0.64
ADORA3 P0DMS8 1/20 0.64
PTGS1 P23219 1/20 0.64
RXFP1 Q9HBX9 1/20 0.64
TUBB4A P04350 4/20 0.59
TUBB P07437 4/20 0.59
TUBA3C P0DPH7 4/20 0.59
TUBA1B P68363 4/20 0.59
TUBA4A P68366 4/20 0.59
TUBB4B P68371 4/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cyclobendazole SCHEMBL1649791 1.00 LMNA (0.65) LMNACYP1A2HIF1AALDH1A1KDR
Flubendazole SCHEMBL28086273 0.91 KDR (0.82) LMNACYP1A2HIF1AALDH1A1KDR
Cyclobendazole SCHEMBL159525 0.90 LMNA (0.53) LMNACYP1A2HIF1AALDH1A1KDR
SCHEMBL5061886 0.86 SMN1; SMN2 (0.51) LMNACYP1A2HIF1AALDH1A1KDR
Cyclobendazole SCHEMBL28086205 0.85 LMNA (0.71) LMNACYP1A2HIF1AALDH1A1KDR
SCHEMBL18762324 0.83 LMNA (0.77) LMNACYP1A2HIF1AALDH1A1KDR
Flubendazole SCHEMBL20815724 0.82 KDR (0.69) LMNACYP1A2HIF1AALDH1A1KDR
SCHEMBL14491215 0.81 LMNA (0.59) LMNACYP1A2HIF1AALDH1A1KDR
Fenbendazole SCHEMBL8009005 0.79 LMNA (0.65) LMNACYP1A2HIF1AALDH1A1KDR
SCHEMBL28601663 0.79 LMNA (0.63) LMNACYP1A2HIF1AALDH1A1KDR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120018779-A Feed and method for controlling infection of central filarial in mammals 碗中动物健康公司 2025-05-16 CN claimed
CN-120018779-A Feed and method for controlling infection of central filarial in mammals 碗中动物健康公司 2025-05-16 CN disclosed