SCHEMBL31546786

SCHEMBL31546786

COc1cc2ccccc2cc1-c1cn(-c2ccc3c(c2)CN(C2CCC(=O)NC2=O)C3=O)nn1

nearest known ligand 0.48

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ CRBN Q96SW2 9/20 0.48
▸ CSNK1A1 P48729 4/20 0.47
▸ IKZF2 Q9UKS7 12/20 0.45
▸ WIZ O95785 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31546838 0.93 WIZ (0.48) CRBNCSNK1A1IKZF2WIZ
SCHEMBL31546865 0.91 CRBN (0.53) CRBNCSNK1A1IKZF2WIZ
SCHEMBL31546765 0.90 WIZ (0.52) CRBNCSNK1A1IKZF2WIZ
SCHEMBL31546827 0.86 CRBN (0.48) CRBNCSNK1A1IKZF2
SCHEMBL31546687 0.86 CRBN (0.48) CRBNCSNK1A1IKZF2WIZ
SCHEMBL31546910 0.85 CRBN (0.51) CRBNCSNK1A1IKZF2WIZ
SCHEMBL31546851 0.85 CRBN (0.56) CRBNCSNK1A1IKZF2
SCHEMBL31546855 0.85 IKZF2 (0.49) CRBNIKZF2
SCHEMBL31546864 0.85 CRBN (0.48) CRBNCSNK1A1IKZF2WIZ
SCHEMBL31546770 0.84 CRBN (0.58) CRBNCSNK1A1IKZF2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025076285-A1 COMPOUNDS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND METHODS OF USING THE SAME DELPHIA THERAPEUTICS, INC. (US) 2025-04-10 — — WO disclosed
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