SCHEMBL31546706

SCHEMBL31546706

COc1cnc(-c2cn(-c3ccc4c(c3)CN(C3CCC(=O)NC3=O)C4=O)nn2)c(OC)c1

nearest known ligand 0.51

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ IKZF2 Q9UKS7 13/20 0.51
▸ WIZ O95785 2/20 0.48
▸ CRBN Q96SW2 9/20 0.47
▸ CSNK1A1 P48729 4/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31546765 0.89 WIZ (0.52) IKZF2WIZCRBNCSNK1A1
SCHEMBL31546839 0.89 IKZF2 (0.53) IKZF2WIZCRBNCSNK1A1
SCHEMBL31546894 0.88 IKZF2 (0.56) IKZF2WIZCRBNCSNK1A1
SCHEMBL31546925 0.86 IKZF2 (0.48) IKZF2WIZCRBNCSNK1A1
SCHEMBL31546910 0.86 CRBN (0.51) IKZF2WIZCRBNCSNK1A1
SCHEMBL31546766 0.85 IKZF2 (0.51) IKZF2WIZCRBNCSNK1A1
SCHEMBL31546865 0.85 CRBN (0.53) IKZF2WIZCRBNCSNK1A1
SCHEMBL31546786 0.84 CRBN (0.48) IKZF2WIZCRBNCSNK1A1
SCHEMBL31546838 0.84 WIZ (0.48) IKZF2WIZCRBNCSNK1A1
SCHEMBL31546864 0.83 CRBN (0.48) IKZF2WIZCRBNCSNK1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025076285-A1 COMPOUNDS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND METHODS OF USING THE SAME DELPHIA THERAPEUTICS, INC. (US) 2025-04-10 — — WO disclosed
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