Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | PTGER3 | P43115 | 3/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.40 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | CDC7 | O00311 | 2/20 | 0.39 |
| ▸ | BTK | Q06187 | 6/20 | 0.39 |
| ▸ | PLK4 | O00444 | 1/20 | 0.38 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.38 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.38 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.38 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.38 |
| ▸ | PAK4 | O96013 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | PRKCG | P05129 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31547667 | 0.86 | KDM4E (0.61) | KDM4EALDH1A1GAASMN1; SMN2RXFP1 | |
| SCHEMBL25148578 | 0.86 | KDM4E (0.61) | KDM4EALDH1A1GAASMN1; SMN2RXFP1 | |
| SCHEMBL17844558 | 0.76 | KDM4E (0.51) | KDM4EALDH1A1GAASMN1; SMN2RXFP1 | |
| SCHEMBL17883343 | 0.76 | KDM4E (0.74) | KDM4EALDH1A1GAASMN1; SMN2RXFP1 | |
| SCHEMBL31547623 | 0.73 | MCL1 (0.50) | KDM4EALDH1A1GAASMN1; SMN2RXFP1 | |
| SCHEMBL23381853 | 0.71 | BTK (0.34) | ALDH1A1PTGER3BRD4CDC7BTK | |
| SCHEMBL5791701 | 0.71 | SPR (0.54) | KDM4EALDH1A1GAASMN1; SMN2RXFP1 | |
| SCHEMBL25149514 | 0.70 | LMNA (0.44) | KDM4EALDH1A1GAASMN1; SMN2RXFP1 | |
| SCHEMBL31547676 | 0.70 | PTGER3 (0.44) | KDM4EALDH1A1GAAPTGER3BRD4 | |
| SCHEMBL8069141 | 0.70 | GAA (0.51) | KDM4EALDH1A1GAASMN1; SMN2RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025073792-A1 | WRN INHIBITORY COMPOUNDS | FORX THERAPEUTICS AG (CH) | 2025-04-10 | — | — | WO | disclosed |