Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
| ▸ | XDH | P47989 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | OXTR | P30559 | 1/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.41 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.39 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.39 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8069138 | 0.78 | HTT (0.44) | KDM4EALDH1A1SMN1; SMN2XDHNPC1 | |
| SCHEMBL7645797 | 0.74 | XDH (0.44) | GAAALDH1A1XDHHTTSIRT2 | |
| SCHEMBL17844558 | 0.73 | KDM4E (0.51) | GAAKDM4EALDH1A1SMN1; SMN2RXFP1 | |
| SCHEMBL17883343 | 0.73 | KDM4E (0.74) | GAAKDM4EALDH1A1SMN1; SMN2RXFP1 | |
| SCHEMBL17341985 | 0.71 | PARP10 (0.65) | KDM4EALDH1A1RXFP1NPC1MAPT | |
| SCHEMBL31547653 | 0.70 | KDM4E (0.44) | GAAKDM4EALDH1A1SMN1; SMN2RXFP1 | |
| SCHEMBL9198133 | 0.70 | SIRT2 (0.51) | GAAKDM4EALDH1A1SMN1; SMN2XDH | |
| Hydrochloric Acid SCHEMBL29245573 | 0.70 | PARP10 (0.62) | KDM4EALDH1A1RXFP1MAPTNR1H4 | |
| SCHEMBL4687529 | 0.69 | PARP15 (0.59) | GAAALDH1A1SMN1; SMN2XDHNPC1 | |
| SCHEMBL20851318 | 0.68 | MAPT (0.58) | GAAKDM4EALDH1A1SMN1; SMN2XDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6046216-A | USEFUL TO INHIBIT THE GROWTH OF NEOPLASTIC CELLS. | CELL PATHWAYS, INC. (US) | 2000-04-04 | — | — | US | disclosed |
| US-5254571-A | Bronchodilators, antiallergens | SMITH KLINE & FRENCH LABORATORIES LTD. (GB) | 1993-10-19 | — | — | US | disclosed |