Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.51 |
| ▸ | PARK7 | Q99497 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | GSK3A | P49840 | 1/20 | 0.46 |
| ▸ | GSK3B | P49841 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | DAO | P14920 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18951821 | 0.84 | SIGMAR1 (0.54) | SIGMAR1MAPTKDM4EALDH1A1HPGD | |
| SCHEMBL5449024 | 0.80 | SIGMAR1 (0.54) | SIGMAR1MAPTKDM4EALDH1A1 | |
| SCHEMBL5439934 | 0.79 | SIGMAR1 (0.50) | SIGMAR1 | |
| SCHEMBL16474466 | 0.79 | ALDH1A1 (0.53) | MAPTKDM4EALDH1A1GSK3AGSK3B | |
| SCHEMBL5439611 | 0.75 | GSK3A (0.47) | SIGMAR1KDM4EALDH1A1GSK3AGSK3B | |
| SCHEMBL4665263 | 0.73 | BRD4 (0.51) | PARK7MAPTKDM4EALDH1A1GSK3A | |
| SCHEMBL5445050 | 0.73 | HRH3 (0.55) | SIGMAR1MAPTKDM4EALDH1A1NPC1 | |
| SCHEMBL13150788 | 0.72 | SIGMAR1 (0.88) | SIGMAR1 | |
| SCHEMBL22831428 | 0.72 | KDM4E (0.45) | KDM4EALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL16474464 | 0.71 | DRD2 (0.44) | SIGMAR1PARK7MAPTALDH1A1GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116134025-B | Amide phosphine oxide derivative and preparation method and application thereof | 浙江海正药业股份有限公司 | 2025-04-04 | — | — | CN | disclosed |