Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 3/20 | 0.40 |
| ▸ | GABRP | O00591 | 1/20 | 0.39 |
| ▸ | GABRD | O14764 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.39 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.39 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.39 |
| ▸ | GABRE | P78334 | 1/20 | 0.39 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.39 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.39 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.39 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.39 |
| ▸ | AURKA | O14965 | 6/20 | 0.38 |
| ▸ | RPS6KB1 | P23443 | 6/20 | 0.38 |
| ▸ | PDPK1 | O15530 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3140045 | 0.89 | NAMPT (0.43) | NAMPTGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL3144699 | 0.87 | NAMPT (0.39) | NAMPTGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL3156484 | 0.87 | F2 (0.40) | NAMPTGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL3149495 | 0.85 | NAMPT (0.40) | NAMPTGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL3153906 | 0.83 | F2 (0.46) | NAMPTGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL3144720 | 0.81 | HDAC1 (0.39) | NAMPTGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL3153349 | 0.81 | NAMPT (0.40) | NAMPTGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL3153093 | 0.81 | F2 (0.40) | NAMPTGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL3148803 | 0.81 | VNN1 (0.41) | NAMPTGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL3149776 | 0.80 | NAMPT (0.43) | NAMPTGABRPGABRDGABRA1GABRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100076015-A1 | Aminopyridine Derivatives | VANTIA LIMITED (GB) | 2010-03-25 | — | — | US | disclosed |
| WO-2009133348-A1 | AMINOPYRIDINE DERIVATIVES | VANTIA LIMITED (GB) | 2009-11-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100076015-A1 | Aminopyridine Derivatives | CHRM1, ARG1, ARG2 | NAMPT 1657/4885GABRP 1565/4885GABRD 1915/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.