Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.48 |
| ▸ | PDE10A | Q9Y233 | 4/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.39 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.38 |
| ▸ | PI4KA | P42356 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11389023 | 0.81 | ATM (0.53) | CYP1A2CYP2A6PDE10AATML3MBTL1 | |
| SCHEMBL11322378 | 0.81 | PDE10A (0.46) | CYP1A2CYP2A6PDE10AATML3MBTL1 | |
| SCHEMBL10544101 | 0.81 | KCNH2 (0.60) | CYP1A2CYP2A6PDE10AATML3MBTL1 | |
| SCHEMBL11395049 | 0.79 | PDE10A (0.44) | CYP1A2CYP2A6PDE10AATML3MBTL1 | |
| SCHEMBL14479273 | 0.79 | L3MBTL1 (0.45) | CYP1A2CYP2A6PDE10AL3MBTL1PIK3CD | |
| SCHEMBL873512 | 0.78 | CYP1A2 (0.54) | CYP1A2CYP2A6PDE10AATML3MBTL1 | |
| SCHEMBL10667109 | 0.78 | ALDH1A1 (0.47) | CYP1A2CYP2A6PDE10AATML3MBTL1 | |
| SCHEMBL18103467 | 0.78 | CYP1A2 (0.41) | CYP1A2CYP2A6PDE10APOLBPIK3CD | |
| SCHEMBL28931171 | 0.77 | ATM (0.44) | CYP1A2CYP2A6PDE10AATML3MBTL1 | |
| SCHEMBL11371036 | 0.76 | PDE10A (0.44) | CYP1A2PDE10ANPC1RAB9APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1555257-B1 | PROCESS FOR PRODUCING AROMATIC NITRILE COMPOUND | IHARA CHEMICAL IND CO (JP) | 2010-01-20 | — | — | EP | disclosed |
| CN-100339360-C | Process for producing aromatic nitrile compound | IHARA CHEMICAL IND CO (JP) | 2007-09-26 | — | — | CN | disclosed |
| US-7262316-B2 | Process for producing aromatic nitrile compound | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2007-08-28 | — | — | US | disclosed |
| US-20060069282-A1 | Process for producing aromatic nitrile compound | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2006-03-30 | — | — | US | disclosed |
| CN-1714074-A | Method for producing aromatic nitrile compound | IHARA CHEMICAL IND CO (JP) | 2005-12-28 | — | — | CN | disclosed |
| EP-1555257-A1 | PROCESS FOR PRODUCING AROMATIC NITRILE COMPOUND | IHARA CHEMICAL INDUSTRY Co., Ltd. (JP) | 2005-07-20 | — | — | EP | disclosed |
| US-4287197-A | ALSO USEFUL AS ANALGESICS, ANTIPYRETICS AND ANTIINFLAMMATORY AGENTS | RHONE-POULENC INDUSTRIES (FR) | 1981-09-01 | — | — | US | disclosed |
| US-4261992-A | ANALGESIC, ANTIINFLAMMATORY, ANTIPYRETIC | RHONE POULENC INDUSTRIES (FR) | 1981-04-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060069282-A1 | Process for producing aromatic nitrile compound | ODC1, ALKBH3, GNMT | CYP1A2 219/4885CYP2A6 2434/4885PDE10A 3001/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.