SCHEMBL3155189

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL9525882	0.82	TGFBR1 (0.46)	ADORA3NPC1RAB9ANPSR1GGPS1
	SCHEMBL792707	0.82	ADORA3 (0.44)	ADORA3NPC1RAB9ANPSR1GGPS1
	SCHEMBL24803763	0.79	ADORA3 (0.42)	ADORA3NPC1RAB9ANPSR1GGPS1
	SCHEMBL9075915	0.77	EPHB3 (0.41)	ADORA3NPC1RAB9ANPSR1GGPS1
	SCHEMBL21808337	0.73	HTR2A (0.42)	ADORA3NPC1RAB9ANPSR1GGPS1
	SCHEMBL18766632	0.72	MAP3K14 (0.41)	FLT3HTR6POLBTSHRKDM4E
	SCHEMBL17102638	0.72	NPC1 (0.41)	ADORA3NPC1RAB9ANPSR1GGPS1
	SCHEMBL4557281	0.71	AKR1B1 (0.52)	—
	SCHEMBL3313454	0.71	MIF (0.53)	ADORA3NPC1RAB9ANPSR1GGPS1
	SCHEMBL4557262	0.70	PIK3CA (0.39)	ADORA3NPC1RAB9ANPSR1FLT3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.