Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.38 |
| ▸ | PARP1 | P09874 | 3/20 | 0.38 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.36 |
| ▸ | NPY5R | Q15761 | 5/20 | 0.35 |
| ▸ | RORC | P51449 | 3/20 | 0.34 |
| ▸ | DRD2 | P14416 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31552773 | 0.85 | EPHX2 (0.45) | EPHX2RIPK1PARP1PARP2NPY5R | |
| SCHEMBL31552625 | 0.80 | EPHX2 (0.46) | EPHX2RIPK1PARP1PARP2NPY5R | |
| SCHEMBL31552619 | 0.74 | EPHX2 (0.59) | EPHX2PARP1PARP2NPY5RRORC | |
| SCHEMBL20198791 | 0.68 | EPHX2 (0.51) | EPHX2DRD2KMT2AL3MBTL1KCNA3 | |
| SCHEMBL22737131 | 0.67 | RIPK1 (0.52) | RIPK1 | |
| SCHEMBL28714243 | 0.67 | RIPK1 (0.52) | RIPK1 | |
| SCHEMBL31287305 | 0.67 | EPHX2 (0.79) | EPHX2DRD2KMT2AL3MBTL1KCNA3 | |
| SCHEMBL22482343 | 0.67 | EPHX2 (0.79) | EPHX2DRD2KMT2AL3MBTL1KCNA3 | |
| SCHEMBL29675335 | 0.67 | EPHX2 (0.79) | EPHX2DRD2KMT2AL3MBTL1KCNA3 | |
| SCHEMBL29675261 | 0.67 | EPHX2 (0.79) | EPHX2DRD2KMT2AL3MBTL1KCNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025077767-A1 | NOVEL I-TYPE TOPOISOMERASE INHIBITOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海翊维康医药有限责任公司 | 2025-04-17 | — | — | WO | disclosed |