Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 2/20 | 0.38 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.38 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.37 |
| ▸ | DRD2 | P14416 | 2/20 | 0.35 |
| ▸ | BTK | Q06187 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.34 |
| ▸ | RORC | P51449 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31552773 | 0.86 | EPHX2 (0.45) | EPHX2RIPK1PARP1PARP2NPY5R | |
| SCHEMBL31552605 | 0.80 | EPHX2 (0.40) | EPHX2RIPK1PARP1PARP2NPY5R | |
| SCHEMBL31552619 | 0.80 | EPHX2 (0.59) | EPHX2PARP1PARP2NPY5RDRD2 | |
| SCHEMBL415357 | 0.74 | EPHX2 (0.42) | EPHX2DRD2BTKGAAKDM1A | |
| SCHEMBL27821186 | 0.73 | GAA (0.38) | EPHX2PARP1PARP2BTKGAA | |
| SCHEMBL22737131 | 0.72 | RIPK1 (0.52) | RIPK1GAA | |
| SCHEMBL28714243 | 0.72 | RIPK1 (0.52) | RIPK1GAA | |
| SCHEMBL31287305 | 0.72 | EPHX2 (0.79) | EPHX2DRD2BTKKDM1AMAOB | |
| SCHEMBL22482343 | 0.72 | EPHX2 (0.79) | EPHX2DRD2BTKKDM1AMAOB | |
| SCHEMBL29675335 | 0.72 | EPHX2 (0.79) | EPHX2DRD2BTKKDM1AMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025077767-A1 | NOVEL I-TYPE TOPOISOMERASE INHIBITOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海翊维康医药有限责任公司 | 2025-04-17 | — | — | WO | disclosed |